Zymeworks Inc.

Zymeworks Inc.

ZYME
Zymeworks Inc.US flagNASDAQ Global Select
24.11
USD
-0.43
- -
1.77BMarket Cap
Zymeworks Inc.
ZYME
(NASDAQ Global Select)

Recent

price

24.35

P/E

ratio

- -

div

yld

- -

ROIC.AI

2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
TTM
FRC
0.08
0.49
0.56
2.44
1.82
0.78
0.77
0.52
6.33
1.1
1.01
1.41
1.08
Revenue per Share
-0.65
-0.97
-1.74
-0.51
-1.26
-3.83
-3.58
-4.11
1.91
-1.72
-1.62
-1.08
-1.36
Basic EPS, GAAP
-0.37
-1.16
-2.07
-0.14
0.71
-2.52
-3.13
-3.99
2.01
-1.78
-1.49
-0.47
-1.03
Free Cash Flow per Basic Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Dividend per Share
- -
0.99
0.45
5.38
6.01
4.19
5.02
1.13
5.34
4.78
2.55
2.12
0.83
Book Value per Share
- -
0.91
-1.2
4.01
5.1
5.52
7.44
4.18
6.97
6.21
4.25
3.38
2
Tangible Book Value per Share
20
20
20
21
29
38
50
52
65
69
76
75
75
Basic Weighted Avg Shares
2
10
11
52
53
30
39
27
412
76
76
106
81
Sales/Revenue/Turnover
-763.35
-206.63
-336.96
-15.32
-62.93
-509.49
-481.25
-808.37
31.63
-181.56
-157.03
-87.33
-140.23
Operating Margin (%)
- -
- -
1
3
4
7
10
10
12
17
11
11
11
Depreciation Expense
-13
-19
-34
-10
-37
-145
-181
-212
124
-119
-123
-81
-103
Net Income, GAAP
- -
- -
- -
- -
- -
- -
- -
- -
8.05
- -
- -
- -
- -
Effective Tax Rate (%)
-774.97
-198.45
-307.1
-20.1
-68.95
-492.27
-463.54
-794.01
30.14
-156.13
-160.8
-76.56
-126.33
Profit Margin (%)
- -
13
30
78
174
229
369
216
449
357
212
206
350
Working Capital
- -
- -
4
- -
- -
6
6
31
25
22
16
15
14
LT Debt
- -
18
9
116
180
246
410
249
493
465
339
269
164
Total Equity
- -
- -
- -
- -
- -
- -
- -
- -
29.28
- -
- -
- -
- -
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
53.31
- -
- -
- -
- -
Return on Capital (%)
- -
-194.79
-241.01
-17.75
-25.29
-87.01
-87.55
-136.23
61.25
-35.05
-46.96
-45.91
-85.62
Return on Common Equity (%)

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
3
3
3
LT Borrowings
- -
- -
- -
LT Finance Leases
16
15
14
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
76
75
74
Market Capitalization
1,285
1,985
1,885

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
292
249
386
Cash, Cash Equivalents & STI
252
229
365
Accounts Receivable, Net
29
5
5
Inventories
- -
- -
- -
Total Current Liabilities
42
42
36
Payables & Accruals
31
27
30
ST Debt
3
3
3
Deferred Revenue
3
2
2

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
130.58%
1.02%
-20.74%
Free Cash Flow
-173.08%
-80.59%
-68.74%
Net Income, GAAP
21.31%
-73.46%
-33.88%
Sales/Revenue/Turnover
174.63%
274.44%
38.87%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
10
19
16
31
76
2025
27
49
28
3
106
2026
2
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.42
-0.49
-0.39
-0.31
-1.62
2025
-0.3
0.03
-0.26
-0.55
-1.08
2026
-0.59
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -
Business
Zymeworks Inc. (Nasdaq: ZYME) is a clinical-stage biotechnology company that develops and commercializes multifunctional biotherapeutics targeting difficult-to-treat cancers and other diseases. The company engineers Azymetric and Zymabod platforms to create bispecific antibodies and multispecific antibody-based molecules; its product candidates include zanidatamab, a HER2-targeting bispecific antibody in Phase 3 trials for biliary tract cancer partnered with Jazz Pharmaceuticals, as well as ZW171, ZW220, and other preclinical and early-stage assets targeting solid tumors and hematologic malignancies. Zymeworks offers contract research and development services through its subsidiaries, focusing on protein engineering and therapeutic design for oncology and autoimmune indications. Founded in 2010 and headquartered in Vancouver, Canada, the company operates primarily in North America with clinical trials and partnerships extending to Europe and Asia. In the last two years, Zymeworks completed a significant strategic transaction with Iconic Therapeutics in 2024, acquiring full global rights to zanidatamab and related HER2-targeted programs following Jazz Pharmaceuticals' return of rights in late 2023, enabling accelerated independent development. The company raised approximately CAD 92 million through a public offering in 2024 to fund zanidatamab's Phase 3 HERIZON-BTC-01 trial and other pipeline advancement. Zymeworks also advanced ZW171 into a Phase 1 trial in 2025 for advanced or metastatic solid tumors, marking a key expansion of its ROR1-targeted portfolio, while streamlining operations to focus on high-potential clinical assets amid a challenging biotech funding environment.

Company News

APIChat
  • Zymeworks: Royalty-Backed Biotech Flywheel With Underappreciated ADC Optionality

  • Zymeworks Announces Share Repurchase Program of up to $125 Million of its Common Stock

  • Zymeworks Announces Participation in Upcoming Investor Conferences

  • Zymeworks Q1 Earnings Call Highlights

  • Zymeworks Inc. (ZYME) Q1 2026 Earnings Call Transcript

  • Zymeworks Inc. (ZYME) Reports Q1 Loss, Misses Revenue Estimates

  • Zymeworks Provides Corporate Update and Reports First Quarter 2026 Financial Results

  • Zymeworks (NASDAQ:ZYME) and ADVANZ PHARMA (OTCMKTS:CXRXF) Financial Contrast

  • Zymeworks Highlights Royalty-Fueled Pivot at Bloom Burton, Eyes Multibillion-Dollar Ziihera

  • Zymeworks Inc. (NASDAQ:ZYME) Receives Consensus Rating of “Moderate Buy” from Analysts

  • Zymeworks Presents New Phase 1 Data for ZW191, a Folate Receptor Alpha-Targeting ADC at AACR Annual Meeting 2026

  • Zymeworks Presents New Preclinical Data at AACR 2026 Highlighting Broad Antibody-Drug Conjugate Programs Including Novel RAS-Targeting Platform

  • Zymeworks to Report First Quarter 2026 Financial Results and Host Conference Call on May 7, 2026

  • Zymeworks Announces Additional Leadership Appointments to Advance Next Phase of Growth

  • Capricorn Fund Managers Ltd Buys Shares of 1,022,840 Zymeworks Inc. $ZYME

  • Neoleukin Therapeutics (NASDAQ:NLTX) & Zymeworks (NASDAQ:ZYME) Critical Contrast

  • Zymeworks Appoints Kristin Stafford as Chief Financial Officer

  • Zymeworks Receives U.S. FDA Fast Track Designation for ZW191, an FRα-Targeting Antibody-Drug Conjugate

  • Zymeworks Announces Participation in Upcoming Investor Conferences

  • Zymeworks Announces Presentations for Ziihera® (zanidatamab-hrii) at 2026 AACR Annual Meeting