Zymeworks Inc.

Zymeworks Inc.

ZYME
Zymeworks Inc.US flagNASDAQ Global Select
26.81
USD
-0.69
- -
1.97BMarket Cap
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
0.08
0.49
0.56
2.44
1.82
0.78
0.77
0.52
6.33
1.1
1.01
1.41
0.5
Basic EPS, GAAP
-0.65
-0.97
-1.74
-0.51
-1.26
-3.83
-3.58
-4.11
1.91
-1.72
-1.62
-1.08
-2.01
Free Cash Flow per Basic Share
-0.37
-1.16
-2.07
-0.14
0.71
-2.52
-3.13
-3.99
2.01
-1.78
-1.49
-0.47
-1.62
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
- -
0.93
0.46
4.58
5.64
6.21
8.9
5.34
7.82
6.63
4.91
3.57
1.12
Tangible Book Value per Share
- -
0.92
-1.2
3.35
4.64
5.31
8.15
4.62
7.21
6.1
4.67
3.39
0.94
Basic Weighted Avg Shares
20
20
20
21
29
38
50
52
65
69
76
75
75
Sales/Revenue/Turnover
2
10
11
52
53
30
39
27
412
76
76
106
37
Operating Margin (%)
-763.35
-206.63
-336.96
-15.32
-62.93
-509.49
-481.25
-808.37
31.63
-181.56
-157.03
-87.33
-418.77
Depreciation Expense
- -
- -
1
3
4
7
10
10
12
17
11
11
9
Net Income, GAAP
-13
-19
-34
-10
-37
-145
-181
-212
124
-119
-123
-81
-150
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
8.05
- -
- -
- -
- -
Profit Margin (%)
-774.97
-198.45
-307.1
-20.1
-68.95
-492.27
-463.54
-794.01
30.14
-156.13
-160.8
-76.56
-404
Working Capital
- -
13
30
78
174
229
369
216
449
357
212
206
251
LT Debt
- -
- -
4
- -
- -
6
6
31
25
22
16
15
13
Total Equity
- -
18
9
116
180
246
410
249
493
465
339
269
80
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
29.28
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
30.99
- -
- -
- -
- -
Return on Common Equity (%)
- -
-210.21
-252.04
-17.42
-24.62
-68.25
-55.08
-64.29
33.51
-24.78
-30.54
-26.72
-72.31

Capital Structure

FRC

•

in mil. unless spec.
Dec'25
Mar'26
Jun'26
ST Debt
3
3
3
LT Borrowings
- -
- -
- -
LT Finance Leases
15
14
13
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
75
74
72
Market Capitalization
1,980
1,844
1,881

Working Capital

FRC

•

in mil. unless spec.
Dec'25
Mar'26
Jun'26
Total Current Assets
249
386
298
Cash, Cash Equivalents & STI
229
365
271
Accounts Receivable, Net
5
5
6
Inventories
- -
- -
- -
Total Current Liabilities
42
36
47
Payables & Accruals
27
30
28
ST Debt
3
3
3
Deferred Revenue
2
2
16

Growth Rates

FRC

•

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
130.58%
1.02%
-20.74%
Free Cash Flow
-173.08%
-80.59%
-68.74%
Net Income, GAAP
21.31%
-73.46%
-33.88%
Sales/Revenue/Turnover
174.63%
274.44%
38.87%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
10
19
16
31
76
2025
27
49
28
3
106
2026
2
5
- -
- -
- -

Quarterly Earnings Per Share

FRC

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.42
-0.49
-0.39
-0.31
-1.62
2025
-0.3
0.03
-0.26
-0.55
-1.08
2026
-0.59
-0.62
- -
- -
- -

Quarterly Dividends Per Share

FRC

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

CEO
Kenneth H. Galbraith
Full Time Employees
231
Sector
Healthcare
Industry
Biotechnology
Address
108 Patriot Drive Middletown DE United States of America 19709
IPO Date
Apr 28, 2017
Business
Zymeworks Inc. (Nasdaq: ZYME) is a clinical-stage biotechnology company that develops and commercializes multifunctional biotherapeutics targeting difficult-to-treat cancers and other diseases. The company engineers Azymetric and Zymabod platforms to create bispecific antibodies and multispecific antibody-based molecules; its product candidates include zanidatamab, a HER2-targeting bispecific antibody in Phase 3 trials for biliary tract cancer partnered with Jazz Pharmaceuticals, as well as ZW171, ZW220, and other preclinical and early-stage assets targeting solid tumors and hematologic malignancies. Zymeworks offers contract research and development services through its subsidiaries, focusing on protein engineering and therapeutic design for oncology and autoimmune indications. Founded in 2010 and headquartered in Vancouver, Canada, the company operates primarily in North America with clinical trials and partnerships extending to Europe and Asia. In the last two years, Zymeworks completed a significant strategic transaction with Iconic Therapeutics in 2024, acquiring full global rights to zanidatamab and related HER2-targeted programs following Jazz Pharmaceuticals' return of rights in late 2023, enabling accelerated independent development. The company raised approximately CAD 92 million through a public offering in 2024 to fund zanidatamab's Phase 3 HERIZON-BTC-01 trial and other pipeline advancement. Zymeworks also advanced ZW171 into a Phase 1 trial in 2025 for advanced or metastatic solid tumors, marking a key expansion of its ROR1-targeted portfolio, while streamlining operations to focus on high-potential clinical assets amid a challenging biotech funding environment.

Company News

  • Zymeworks Completes Acquisition of Theravance Biopharma

  • Zymeworks Inc. (ZYME) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

  • Jupiter Topco LLC Buys New Position in Zymeworks Inc. $ZYME

  • Zymeworks: Transitioning Into A Royalty-Driven Biopharma Platform Post Ziihera Approval

  • Bank of America Corp DE Raises Position in Zymeworks Inc. $ZYME

  • JAZZ Secures FDA Nod for Expanded Use of Ziihera in Gastric Cancer

  • Deutsche Bank AG Buys Shares of 397,190 Zymeworks Inc. $ZYME

  • TBPH Meets Q2 Earnings Estimates, to be Acquired by Zymeworks

  • Zymeworks Inc. (ZYME) Reports Q2 Loss, Beats Revenue Estimates

  • Zymeworks Provides Corporate Update and Reports Second Quarter 2026 Financial Results

  • Zymeworks to Report Second Quarter 2026 Financial Results on August 6, 2026

  • Here's Why Zymeworks Inc. Paid $929M For Theravance Biopharma

  • Theravance Stock Down 3% After Zymeworks Announces Buyout

  • Zymeworks Inc. (ZYME) M&A Call Transcript

  • Zymeworks Targets Long-Term Cash Generation Through Theravance Acquisition

  • Zymeworks strikes $929 million deal for Theravance Biopharma

  • Zymeworks to Acquire Theravance Biopharma, Inc.

  • Gandeeva and Zymeworks Use Cryo-EM to Accelerate Antibody Drug Discovery

  • Zymeworks Presents New Phase 1 Data for Folate Receptor Alpha-Targeting ADC ZW191 at ESMO Gynaecological Cancers Congress 2026

  • Zymeworks Presents New Phase 1 Data for Folate Receptor Alpha-Targeting ADC ZW191 at ESMO Gynaecological Cancers Congress 2026