AC Immune S.A.

AC Immune S.A.

ACIU
AC Immune S.A.US flagNASDAQ Global Market
2.86
USD
-0.07
- -
291.07MMarket Cap
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
0.55
0.9
0.46
0.35
0.11
1.56
0.21
- -
0.05
0.17
0.27
0.04
0.18
Basic EPS, GAAP
0.19
0.47
-0.14
-0.46
-0.82
0.64
-0.86
-0.97
-0.85
-0.64
-0.51
-0.7
-0.43
Free Cash Flow per Basic Share
-0.32
1.01
-0.13
-0.42
-0.74
0.76
-0.85
-0.91
-0.9
-0.72
0.65
-0.7
-0.35
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
0.42
1.28
2.51
2.04
2.63
3.79
3
2.78
2.02
1.62
1.12
0.44
0.35
Tangible Book Value per Share
0.42
1.28
2.51
2.04
2.63
3.79
3
2.17
1.42
1.11
0.62
-0.05
-0.15
Basic Weighted Avg Shares
55
43
50
57
62
71
72
75
84
85
100
101
100
Sales/Revenue/Turnover
30
39
23
20
7
110
15
- -
4
15
27
4
18
Operating Margin (%)
35.41
47.64
-45.04
-111.28
-716.87
40.32
-396.99
- -
-1,800.43
-362.3
-191.8
-1,927.32
-249.59
Depreciation Expense
- -
- -
- -
1
1
2
2
2
2
2
2
3
1
Net Income, GAAP
11
20
-7
-26
-51
45
-62
-73
-71
-54
-51
-70
-43
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
35.5
51.85
-30.57
-130.39
-737.14
41.14
-401.28
- -
-1,798.04
-366.41
-186.44
-1,971.65
-246.49
Working Capital
25
73
145
120
180
275
218
183
117
112
71
2
-7
LT Debt
- -
- -
- -
- -
- -
2
2
2
2
3
4
4
3
Total Equity
23
71
142
117
178
272
215
232
169
161
112
45
35
Return on Invested Capital (%)
- -
39.41
- -
- -
- -
19.64
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
42.89
- -
- -
- -
20.89
- -
- -
- -
- -
- -
- -
-70.05
Return on Common Equity (%)
- -
42.89
-6.65
-20.38
-34.61
20.19
-25.38
-32.63
-35.29
-32.9
-37.31
-89.65
-78.53

Capital Structure

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
ST Debt
1
1
1
LT Borrowings
- -
- -
- -
LT Finance Leases
4
3
3
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
102
102
102
Market Capitalization
253
224
196

Working Capital

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
Total Current Assets
97
80
93
Cash, Cash Equivalents & STI
91
75
75
Accounts Receivable, Net
- -
- -
10
Inventories
- -
- -
- -
Total Current Liabilities
95
92
100
Payables & Accruals
10
8
9
ST Debt
1
1
1
Deferred Revenue
84
84
91

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
5.24%
-22.91%
-60.02%
Free Cash Flow
-59.97%
-82.24%
-207.5%
Net Income, GAAP
-17.16%
4.74%
38.36%
Sales/Revenue/Turnover
- -
- -
-86.92%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
1
25
1
27
2025
1
1
1
- -
4
2026
1
15
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.18
-0.23
0.06
- -
-0.51
2025
-0.19
-0.21
-0.16
- -
-0.7
2026
-0.15
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

CEO
Martin Zügel
Full Time Employees
106
Sector
Healthcare
Industry
Biotechnology
Address
Building B Lausanne VD Switzerland 1015
IPO Date
Sep 23, 2016
Business
AC Immune SA (ACIU), a clinical-stage biopharmaceutical company founded in 2003 and headquartered in Lausanne, Switzerland, discovers, designs and develops precision medicines, therapeutics and diagnostics targeting misfolded proteins underlying neurodegenerative diseases including Alzheimer's disease, Parkinson's disease and NeuroOrphan indications. The company leverages its proprietary SupraAntigen® and Morphomer® technology platforms to advance a diversified pipeline encompassing active immunotherapies such as ACI-24.060 (anti-amyloid beta for Alzheimer's, partnered with Janssen), ACI-7104.056 (anti-alpha-synuclein for early Parkinson's), and ACI-35.030 (anti-Tau for Alzheimer's, partnered with Lilly); therapeutic antibodies; small molecule inhibitors including ACI-19764 (NLRP3), Morphomer®-Tau and alpha-synuclein aggregation inhibitors, and Morphomer®-antibody drug conjugates (morADCs); as well as diagnostic agents like Tau PET tracers. AC Immune operates globally with a focus on clinical-stage programs in Phase 2 and preclinical advancement, deriving validation and non-dilutive funding from strategic alliances with pharmaceutical leaders including Janssen, Takeda and Eli Lilly, which provide over $4.5 billion in potential milestones plus royalties. In September 2025, the company sharpened its pipeline focus on three Phase 2 active immunotherapies and priority small molecule programs targeting NLRP3, Tau and alpha-synuclein, implementing operational efficiencies including a 30% workforce reduction to extend cash runway into Q3 2027; near-term catalysts include interim Phase 2 data from ACI-7104.056 (H2 2025), ACI-24.060 (H1 2026), IND filing for ACI-19764 (H2 2025) and Morphomer® lead declarations.

Company News

  • AC Immune Announces Positive Preliminary Phase 1 Data for NLRP3 Inhibitor ACI-19764

  • AC Immune (ACIU) Beats Q2 Earnings and Revenue Estimates

  • AC Immune First Half 2026 Financial and Corporate Update

  • AC Immune to Showcase Neurodegenerative Disease Pipeline with Three Presentations at AAIC® 2026

  • AC Immune Reports Interim 12-Month Data from Phase 1b/2 ABATE Trial of ACI-24 in Prodromal Alzheimer's Disease

  • AC Immune to Receive Research Grant from Goradia Family for Development of ACI-7104 in Parkinson's Disease

  • AC Immune (ACIU) Forms 'Hammer Chart Pattern': Time for Bottom Fishing?

  • AC Immune Presents New Phase 1 Data Indicating Higher Uptake of TDP-43 PET Tracer ACI-19626 in Patients with ALS

  • Davos Alzheimer's Collaborative Celebrates Andrea Pfeifer, Retiring CEO of AC Immune, for Her Contributions to Alzheimer's Policy, Research and Care

  • AC Immune (ACIU) May Find a Bottom Soon, Here's Why You Should Buy the Stock Now

  • AC Immune Announces Retirement of CEO Dr Andrea Pfeifer at Upcoming AGM

  • AC Immune (ACIU) Reports Q1 Loss, Tops Revenue Estimates

  • AC Immune First Quarter 2026 Financial and Corporate Updates

  • AC Immune Initiates Final Cohort in Ongoing Phase 1b/2 ABATE Trial of Anti-Abeta Active Immunotherapy to Treat Alzheimer's Disease

  • ACIU Stock Rallies 16.3% in a Week: Here's What You Need to Know

  • Is AC Immune (ACIU) Stock Outpacing Its Medical Peers This Year?

  • Why AC Immune Stock Zoomed Almost 15% Higher Today

  • AC Immune Announces Amendment to Morphomer ® Tau License and Collaboration Agreement with Lilly

  • AC Immune (ACIU) Upgraded to Buy: Here's Why

  • Is AC Immune (ACIU) Outperforming Other Medical Stocks This Year?