Alector, Inc.

Alector, Inc.

ALEC
Alector, Inc.US flagNASDAQ Global Select
1.78
USD
-0.17
- -
197.07MMarket Cap
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
0.01
0.07
0.4
0.34
0.27
2.58
1.62
1.16
1.04
0.2
0.17
Basic EPS, GAAP
-0.29
-0.63
-0.76
-1.71
-2.45
-0.45
-1.62
-1.56
-1.23
-1.39
-1.19
Free Cash Flow per Basic Share
-0.3
-0.36
1.84
-1.86
-2.21
3.67
-0.3
-2.23
-2.39
-1.79
-1.64
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-0.58
-1.21
-1.67
-3.56
-5.27
-5.55
-7.03
-8.48
-8.58
-9.44
-9.41
Tangible Book Value per Share
-0.49
-1.02
-1.42
3.15
3.44
3.74
2.6
1.6
1.31
0.3
0.1
Basic Weighted Avg Shares
51
51
68
62
78
80
82
84
97
103
106
Sales/Revenue/Turnover
- -
4
28
21
21
207
134
97
101
21
18
Operating Margin (%)
-3,637.5
-874.94
-206.99
-539.16
-925.08
-18.04
-103.16
-156.33
-144.19
-741.3
-739.7
Depreciation Expense
- -
1
1
6
7
8
8
9
9
10
10
Net Income, GAAP
-15
-32
-52
-105
-190
-36
-133
-130
-119
-143
-125
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
-3,632.21
-869.61
-188.78
-496.65
-901.64
-17.54
-99.77
-134.34
-118.39
-679.16
-680.83
Working Capital
50
206
245
295
353
610
633
388
300
197
174
LT Debt
- -
- -
- -
41
44
40
35
30
34
27
24
Total Equity
-25
-52
-97
195
268
301
214
134
127
31
10
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
9
9
11
LT Borrowings
10
9
8
LT Finance Leases
19
17
16
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
107
110
111
Market Capitalization
297
161
227

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
300
266
215
Cash, Cash Equivalents & STI
291
256
207
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
80
70
41
Payables & Accruals
37
29
24
ST Debt
9
9
11
Deferred Revenue
12
7
7

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
-27.01%
-75.83%
Free Cash Flow
- -
57.29%
-20.37%
Net Income, GAAP
- -
39.04%
20.06%
Sales/Revenue/Turnover
- -
148.65%
-79.07%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
16
15
15
54
101
2025
4
8
3
6
21
2026
1
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.38
-0.4
-0.43
-0.02
-1.23
2025
-0.41
-0.3
-0.34
-0.34
-1.39
2026
-0.21
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Arnon Rosenthal
Full Time Employees
175
Sector
Healthcare
Industry
Biotechnology
Address
131 Oyster Point Boulevard South San Francisco CA United States of America 94080
IPO Date
Feb 7, 2019
Business
Alector, Inc. (Nasdaq: ALEC) is a clinical-stage biotechnology company focused on developing immuno-neurology therapies to counteract the progression of neurodegenerative diseases such as Alzheimer's disease, frontotemporal dementia, Parkinson's disease and Lewy body dementia. Founded in 2013 and headquartered in South San Francisco, California, the company advances a pipeline of antibody, enzyme replacement and siRNA therapeutics leveraging its proprietary Alector Brain Carrier (ABC) technology for enhanced brain delivery; core programs include AL101 (PGRN antibody in Phase 2 for Alzheimer's disease, partnered with GSK), nivisnebart (PGRN x SORT1 antibody in Phase 2 for Alzheimer's), AL002 (TREM2 agonist in Phase 2 for Alzheimer's), AL137 (anti-amyloid beta antibody in preclinical for Alzheimer's), AL050 (GCase-ERT in preclinical for Parkinson's, Gaucher disease and Lewy body dementia), ADP064-ABC (anti-tau siRNA in research for Alzheimer's and frontotemporal dementia), ADP062-ABC (anti-α-synuclein siRNA in research for Parkinson's) and ADP065-ABC (anti-NLRP3 siRNA in research for Alzheimer's and Parkinson's). Alector operates primarily in the United States with global clinical trial activities and strategic collaborations including ongoing partnerships with GSK and historical alliances such as with AbbVie. Recent developments encompass completion of enrollment at approximately 75% in the Phase 2 PROGRESS-AD trial for early Alzheimer's by mid-2025, progression of ABC-enabled candidates targeting clinical entry for ADP037-ABC (anti-amyloid beta) and ADP050-ABC (GCase enzyme) in 2026 pending preclinical results, reporting of $457.2 million in cash reserves as of September 2024 to fund operations through 2026, and mixed clinical outcomes including the failure of partnered latozinemab in a frontotemporal dementia trial in 2025.

Company News

APIChat
  • Alector (ALEC) Reports Q1 Loss, Lags Revenue Estimates

  • Alector Reports First Quarter 2026 Financial Results and Provides Business Update

  • Will Alector (ALEC) Report Negative Q1 Earnings? What You Should Know

  • Alector to Discontinue Phase 2 PROGRESS-AD Trial of Nivisnebart (AL101/GSK4527226) in Early Alzheimer's Disease Following Interim Futility Analysis

  • Alector (ALEC)'s Technical Outlook is Bright After Key Golden Cross

  • Wall Street Turns Bullish on HIMS, TDOC and ALEC as Partnerships Reshape Risk Profiles

  • Alector, Inc. (ALEC) Presents at TD Cowen 46th Annual Health Care Conference Transcript

  • Alector (ALEC) Reports Q4 Loss, Beats Revenue Estimates

  • Alector Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Update

  • Alector to Participate in the TD Cowen 46th Annual Health Care Conference

  • Alector (NASDAQ:ALEC) and Milestone Pharmaceuticals (NASDAQ:MIST) Critical Review

  • INVESTOR ALERT: Levi & Korsinsky is Investigating Alec Stock After its Phase 3 INFRONT-3 Clinical Trial Misses Co-Primary Endpoint

  • Alector, Inc. (NASDAQ:ALEC) Given Average Rating of “Reduce” by Analysts

  • Short Interest in Alector, Inc. (NASDAQ:ALEC) Expands By 35.9%

  • Alector (NASDAQ:ALEC) Trading 4.8% Higher – Here’s Why

  • Alector Appoints Neil Berkley as Chief Financial Officer and Chief Business Officer

  • Alector, Inc. (ALEC) Presents at BofA Securities CNS Therapeutics Virtual Conference 2025 Transcript

  • Alector to Participate in the Bank of America CNS Therapeutics Conference

  • ALEC Investors Have Opportunity to Join Alector, Inc. Fraud Investigation with the Schall Law Firm

  • ALEC Investors Have Opportunity to Join Alector, Inc. Fraud Investigation with the Schall Law Firm