aTyr Pharma, Inc.

aTyr Pharma, Inc.

ATYR
aTyr Pharma, Inc.US flagNASDAQ Global Market
0.50
USD
-0.02
- -
49.04MMarket Cap
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
- -
- -
- -
0.13
1.14
- -
0.37
0.01
- -
- -
- -
Basic EPS, GAAP
-30.09
-34.42
-42.42
-34.2
-26.16
-16.13
-7.03
-1.77
-1.77
-1.6
-0.94
-0.86
- -
-0.73
Free Cash Flow per Basic Share
-24.95
-32.07
-33.11
-31.61
-23.7
-14.79
-5.99
-1.69
-1.74
-1.53
-0.7
-0.93
- -
-0.62
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-119.25
-153.09
-139.75
-127.67
-143.34
-139.59
-96.05
-36.95
-19.51
-14.69
-8.73
-7.16
- -
-6.44
Tangible Book Value per Share
-91.84
-126.49
101.7
37.13
34.86
15.72
6.27
3.44
5.72
2.51
1.69
0.94
- -
0.6
Basic Weighted Avg Shares
1
1
1
2
2
2
3
9
19
28
54
74
- -
96
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
- -
- -
10
- -
10
- -
- -
- -
- -
Operating Margin (%)
- -
- -
- -
- -
- -
- -
-5,445.02
-152.19
- -
-446.79
-15,557.79
-28,899.57
-40,856.32
-38,573.68
Depreciation Expense
1
1
1
1
1
1
1
1
1
2
3
2
2
2
Net Income, GAAP
-20
-24
-48
-58
-48
-35
-24
-16
-34
-45
-50
-64
-74
-70
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
- -
- -
- -
- -
- -
- -
-5,593.13
-155.18
- -
-436.53
-14,274.5
-27,243.83
-39,009.47
-36,857.37
Working Capital
32
6
86
66
77
40
19
30
108
67
87
67
65
56
LT Debt
6
5
2
9
15
8
2
1
- -
11
14
12
11
10
Total Equity
-66
-91
115
63
64
34
21
31
109
71
90
70
67
58
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
1
1
1
LT Borrowings
- -
- -
- -
LT Finance Leases
11
11
10
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
98
98
98
Market Capitalization
64
73
75

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
93
80
68
Cash, Cash Equivalents & STI
90
79
67
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
16
15
12
Payables & Accruals
14
14
10
ST Debt
1
1
1
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
13.39%
42.48%
-3.64%
Free Cash Flow
14.35%
41.19%
-10.29%
Net Income, GAAP
10.9%
39.27%
15.77%
Sales/Revenue/Turnover
- -
- -
-19.15%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.23
-0.23
-0.23
-0.18
-0.86
2025
-0.17
-0.22
-0.26
-0.14
- -
2026
-0.11
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Sanjay S. Shukla
Full Time Employees
56
Sector
Healthcare
Industry
Biotechnology
Address
10240 Sorrento Valley Road San Diego CA United States of America 92121
IPO Date
May 7, 2015
Business
aTyr Pharma, Inc. is a clinical-stage biotechnology company specializing in the discovery and development of innovative medicines based on novel biology, specifically leveraging evolutionary intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation. The company’s core products include a proprietary pipeline of protein compositions derived from 20 tRNA synthetase genes, with a primary focus on efzofitimod (ATYR1923), a first-in-class biologic immunomodulator designed to bind the neuropilin-2 receptor. Efzofitimod targets severe inflammatory lung diseases and interstitial lung disease (ILD), a group of immune-mediated disorders characterized by chronic inflammation and progressive fibrosis of the lungs. In addition to efzofitimod, aTyr Pharma is advancing therapeutic candidates such as ATYR0101, which has moved to IND candidate status for pulmonary fibrosis, and other antibody-based therapies targeting neurological and oncological conditions. Founded in 2008 and headquartered in San Diego, California, aTyr Pharma operates globally, with clinical trial sites spread across the United States, Europe, Japan, and Brazil. The company has established strategic partnerships, including a license agreement with Kyorin Pharmaceutical Co., Ltd. for development and commercialization of efzofitimod in Japan. aTyr’s pipeline focuses on high unmet medical needs such as pulmonary sarcoidosis, systemic sclerosis-related ILD, and fibrotic diseases, deploying its unique platform that uncovers hidden therapeutic intervention points by exploiting extracellular signaling pathways regulated by tRNA synthetases. Significant recent developments for the company include the completion of patient enrollment and last patient visit in its pivotal Phase 3 EFZO-FIT™ study of efzofitimod for pulmonary sarcoidosis, which enrolled 268 patients across 85 centers in nine countries with topline results anticipated by mid-September 2025. The Phase 2 EFZO-CONNECT™ study targeting systemic sclerosis-associated ILD is ongoing with promising interim data showing improvements in skin fibrosis and relevant biomarkers. Furthermore, aTyr Pharma reported $92.9 million in cash and investments as of September 30, 2025, demonstrating solid financial positioning to support its clinical programs. The company plans to meet with the U.S. FDA in the first quarter of 2026 to discuss regulatory pathways following the EFZO-FIT results. aTyr continues to focus on expanding its therapeutic pipeline, advancing antibody candidates like ATYR2810, targeting neuropilin-2 in cancer, and strengthening its intellectual property portfolio based on its tRNA synthetase platform.

Company News

APIChat
  • aTyr Pharma Announces First Quarter 2026 Results and Provides Corporate Update

  • aTyr Pharma to Participate in Upcoming Investor Conferences

  • aTyr Pharma, Inc. (ATYR) Discusses FDA Feedback and Next Steps for Efzofitimod in Pulmonary Sarcoidosis After Phase III Results Transcript

  • aTyr Pharma Revamps Efzofitimod Path With New Phase III Sarcoidosis Trial

  • aTyr Pharma Provides Regulatory and Clinical Update for Efzofitimod in Pulmonary Sarcoidosis Following FDA Type C Meeting

  • aTyr Pharma Spotlights Efzofitimod Phase 3 Learnings, Eyes Mid-April FDA Type C Meeting

  • aTyr Pharma Announces Fourth Quarter and Full Year 2025 Results and Provides Corporate Update

  • aTyr Pharma (NASDAQ:ATYR) Trading Down 2.1% – Should You Sell?

  • aTyr Pharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • aTyr Pharma to Present at the Leerink Partners Global Healthcare Conference

  • aTyr Pharma Announces Scheduling of FDA Type C Meeting to Discuss Efzofitimod Program in Pulmonary Sarcoidosis

  • aTyr Pharma, Inc. (NASDAQ:ATYR) Sees Significant Drop in Short Interest

  • Johnson Fistel Investigates Claims on Behalf of aTyr Pharma, Inc. (ATYR) Shareholders

  • Johnson Fistel Investigates Claims on Behalf of aTyr Pharma, Inc. (ATYR) Shareholders

  • ATYR Deadline: ATYR Investors with Losses Have Opportunity to Lead aTyr Pharma, Inc. Securities Fraud Lawsuit

  • Shareholders that lost money on aTyr Pharma, Inc.(ATYR) Urged to Join Class Action – Contact The Gross Law Firm to Learn More

  • FINAL DEADLINE ALERT: Faruqi & Faruqi, LLP Investigates Claims on Behalf of Investors of aTyr Pharma

  • ATYR DEADLINE ALERT: Hagens Berman Alerts aTyr Pharma (ATYR) Investors of Today's Lead Plaintiff Deadline in Securities Class Action

  • DEADLINE ALERT for MRX, ATYR, and WPP: The Law Offices of Frank R. Cruz Reminds Investors of Class Actions on Behalf of Shareholders

  • ATYR Investors Have Opportunity to Lead aTyr Pharma, Inc. Securities Fraud Lawsuit with the Schall Law Firm