Dyadic International, Inc.

Dyadic International, Inc.

DYAI
Dyadic International, Inc.US flagNASDAQ Capital Market
0.69
USD
-0.09
- -
25.13MMarket Cap
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
0.52
- -
0.01
0.02
0.03
0.05
0.06
0.06
0.09
0.1
0.1
0.12
- -
0.05
Basic EPS, GAAP
-0.01
-0.18
1.91
-0.1
-0.07
-0.21
-0.31
-0.34
-0.47
-0.34
-0.24
-0.2
- -
-0.22
Free Cash Flow per Basic Share
0.14
-0.19
-0.02
-0.17
-0.06
-0.16
-0.21
-0.24
-0.41
-0.28
-0.23
-0.14
- -
-0.17
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-2.39
-2.48
-0.54
-0.69
-0.94
-1.19
-1.53
-1.84
-2.29
-2.59
-2.79
-2.93
- -
-2.83
Tangible Book Value per Share
0.06
-0.08
2.15
1.58
1.73
1.53
1.33
1.04
0.66
0.39
0.2
0.08
- -
-0.01
Basic Weighted Avg Shares
33
34
34
37
29
28
27
27
28
28
29
29
- -
34
Sales/Revenue/Turnover
17
- -
- -
1
1
1
2
2
2
3
3
3
1
2
Operating Margin (%)
2.76
-5,156.2
-1,154.93
-979.6
-972.54
-584.48
-550.53
-621.96
-608.64
-345.21
-282.58
-168.17
-579.88
-422.21
Depreciation Expense
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Net Income, GAAP
- -
-6
66
-4
-2
-6
-8
-9
-13
-10
-7
-6
-7
-7
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
-2.5
-5,655.57
20,837.76
-608.67
-281.61
-439.36
-494.21
-582.13
-543.73
-332.23
-234.42
-166.19
-597.63
-435.9
Working Capital
10
6
66
57
49
42
34
28
18
11
6
7
6
5
LT Debt
8
8
- -
- -
- -
- -
- -
- -
- -
- -
- -
5
5
5
Total Equity
3
-2
74
58
50
42
36
28
18
11
6
2
1
- -
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
- -
- -
- -
LT Borrowings
5
5
5
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
36
36
36
Market Capitalization
37
30
28

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
12
10
8
Cash, Cash Equivalents & STI
9
7
6
Accounts Receivable, Net
- -
- -
1
Inventories
- -
- -
- -
Total Current Liabilities
4
4
3
Payables & Accruals
2
2
2
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
-31.66%
-46.03%
-50.11%
Free Cash Flow
81.4%
5.79%
43.46%
Net Income, GAAP
7.51%
-0.66%
26.78%
Sales/Revenue/Turnover
23.83%
5.35%
-64.74%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
2
1
3
2025
- -
- -
- -
- -
1
2026
1
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.07
-0.07
-0.01
- -
-0.2
2025
-0.07
-0.06
-0.06
- -
- -
2026
-0.05
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Mark A. Emalfarb
Full Time Employees
6
Sector
Healthcare
Industry
Biotechnology
Address
140 Intracoastal Pointe Drive Jupiter FL United States of America 33477-5094
IPO Date
Jan 16, 2008
Website
dyadic.com
Business
Dyadic International, Inc. Dyadic International, Inc. (NASDAQ: DYAI) is a global biotechnology company that develops and commercializes proprietary microbial expression platforms, including the C1 and Dapibus expression systems based on the fungal host Thermothelomyces heterothallica, for the scalable production of high-value recombinant proteins and enzymes; these platforms enable the manufacture of animal-free input proteins for life sciences applications such as research reagents, diagnostics, therapeutics, bioprocess inputs including recombinant human albumin and transferrin, food and nutrition ingredients like non-animal dairy enzymes, and bio-industrial enzymes for biofuels, textiles, specialty chemicals, and cellulosic biomass conversion via products such as the EN3ZYME cocktail. Founded in 1979 and headquartered in Jupiter, Florida, the company originally focused on industrial enzymes and textiles before transitioning to biotechnology, serving customers across life sciences, food and nutrition, and bio-industrial markets worldwide with GRAS-designated, cGMP-capable production validated at scales exceeding 100,000 liters. In 2025, Dyadic Applied BioSolutions rebranded to emphasize applied biotechnology solutions, completed a strategic pivot from R&D to commercial revenue focus with first bulk protein sales, achieved multiple milestones including $1.5 million in payments from its Proliant Health & Biologicals partnership for recombinant human albumin targeting commercial launch in late 2025 or early 2026, advanced collaborations with Inzymes ApS and Fermbox Bio yielding purchase orders and 50/50 profit sharing on EN3ZYME, entered a non-exclusive CRISPR/Cas9 license with ERS Genomics to enhance genetic engineering capabilities, expanded into Japan and South Korea via partnership with Intralink, and conducted a public stock offering to fund product development and marketing.

Company News

APIChat
  • Dyadic and Scripps Research Collaborate on Rapid-Response Hantavirus Antibody and Vaccine Development

  • Dyadic to Participate in the Lytham Partners Spring 2026 Investor Conference on May 28, 2026

  • Skyline Corporate Communications Group, LLC Announces Dyadic Applied BioSolutions to Deliver a Live Presentation at the Skyline Signature Series™ on Wednesday, May 27 at 12:00 PM ET

  • Dyadic Applied BioSolutions Announces Participation in Sidoti Virtual Investor Conference

  • Dyadic Applied BioSolutions Announces Participation in Sidoti Virtual Investor Conference

  • Dyadic International, Inc. (DYAI) Q1 2026 Earnings Call Transcript

  • Dyadic Announces First Quarter 2026 Financial Results and Highlights Recent Company Progress

  • Dyadic to Report Q1 2026 Financial Results and Host Conference Call on Wednesday May 13, 2026

  • Dyadic International, Inc. (DYAI) Q4 2025 Earnings Call Transcript

  • Dyadic Announces 2025 Financial Results and Highlights Recent Company Progress

  • Dyadic Applied BioSolutions Announces Commercial Distribution Partnership with IBT Bioservices

  • Dyadic to Report 2025 Full Year Financial Results and Host Conference Call on Wednesday, March 25, 2026

  • Dyadic and Fermbox Bio Launch First Product Under Expanded Collaboration: Animal-Origin-Free Recombinant DNase I (RNase-Free)

  • Dyadic Applied BioSolutions and Inzymes ApS Announce Planned 2026 Commercialization of Non-Animal Dairy Enzyme Following Achievement of Development Milestone

  • Dyadic Applied BioSolutions and Proliant Health & Biologicals Announce Commercial Launch of Recombinant Human Albumin

  • Dyadic International (NASDAQ:DYAI) Share Price Crosses Below 50 Day Moving Average – Should You Sell?

  • Dyadic and Fermbox Bio Expand Strategic Collaboration to Accelerate Commercialization of Animal-Free Proteins and Enzymes Across Life Science, Food & Nutrition, and Bioindustrial Markets

  • Dyadic Applied BioSolutions Establishes Commercial Partnership to Accelerate Adoption of Dyadic's Recombinant Growth Factors and Media Proteins

  • Dyadic International, Inc. (DYAI) Presents at IAccess Alpha Virtual Best Ideas Winter Investment Conference 2025 Transcript

  • Reviewing Dyadic International (NASDAQ:DYAI) and Kezar Life Sciences (NASDAQ:KZR)