- CEO
- Ronald H. W. Cooper
- Full Time Employees
- 56
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- 4868 Rue Levy Montreal QC Canada H4S 1Z9
- IPO Date
- Feb 1, 2022
- Business
- enGene Holdings Inc. is a clinical-stage biotechnology company that develops non-viral genetic medicines for delivery to mucosal tissues and other organs, with a primary focus on urological cancers including non-muscle invasive bladder cancer (NMIBC). The company offers detalimogene voraplasmid (previously EG-70), a non-viral gene therapy monotherapy evaluated in the ongoing pivotal LEGEND Phase 2 trial for high-risk BCG-unresponsive NMIBC with carcinoma in situ (CIS); and the proprietary DDX (dually derivatized oligochitosan) gene delivery platform, which enables localized, re-dosable delivery of gene cargos such as DNA and RNA to mucosal tissues in the bladder, lung, gastrointestinal tract, and urinary tract. Founded in 1999 and headquartered in Montreal, Quebec, Canada, with U.S. operations in Boston, Massachusetts, enGene Holdings operates through its subsidiary enGene, Inc. and targets patients with high unmet needs in oncology, particularly those unresponsive to standard BCG therapy. Recent developments include a $60 million private placement financing in October 2024 with investors such as Deep Track Capital, Cormorant Asset Management, Forbion, OrbiMed, Sphera Healthcare, Vestal Point Capital, and Venrock Healthcare Capital Partners to support detalimogene development, pre-commercial activities, DDX platform expansion, and operations into 2027; a prior oversubscribed $200 million private placement in February 2024; and the adoption of the 2025 Employee Stock Purchase Plan in June 2025 along with inducement stock option awards.