- Sector
- Healthcare
- Industry
- Medical - Pharmaceuticals
- Address
- United States of America
- IPO Date
- Jun 9, 1992
- Business
- Express Scripts Holding Company, a subsidiary of The Cigna Group since its $67 billion acquisition in December 2018, provides pharmacy benefit management services to health plans, employers, government programs and other clients in the United States. The company offers network-pharmacy claims processing; home delivery pharmacy through Express Scripts Pharmacy; specialty pharmacy services via Accredo; benefit-design consultation; drug utilization review and formulary management; medical and drug data analysis; and related solutions including SafeGuardRx programs for high-cost categories such as oncology, inflammatory conditions, diabetes and hepatitis. It operates a national network of over 65,000 retail pharmacies, serves major clients including the U.S. Department of Defense's Tricare program and Centene Corporation, and maintains headquarters in St. Louis, Missouri, where it was founded in 1986. Recent developments include a multi-year strategic partnership with Centene effective January 2024 to manage pharmacy benefits for approximately 20 million members; a collaboration with CPESN USA announced in 2024 to enhance care coordination for Medicare beneficiaries with hypertension and diabetes while expanding access to independent pharmacies; the launch of Express Scripts ClearNetwork in early 2024 offering clients a transparent cost-plus pricing model for brand, generic and specialty drugs using benchmarks like Predictive Acquisition Cost; and a transition announced in October 2025 to a point-of-sale rebate model for commercial clients that passes negotiated savings directly to members at the pharmacy counter, eliminating post-sale rebates and projecting average 30% savings on brand-name medications.