- CEO
- Filip Jan Jelen
- Full Time Employees
- 7
- Sector
- Health technology
- Industry
- Biotechnology
- Address
- Wroclaw Poland
- IPO Date
- Dec 11, 2018
- Business
- MultiQure S.A. is a biotechnology company that discovers and develops biological drugs and RNA interference (RNAi) gene therapies for severe neurodegenerative conditions, rare genetic diseases, and oncological disorders. The company focuses on developing disease-modifying treatments through proprietary drug discovery platforms and advanced genetic therapeutic pipelines, providing a specialized portfolio that includes allele-selective RNAi gene therapies engineered to silence mutant huntingtin (HTT) transcripts while preserving wild-type expression for Huntington's disease and other polyglutamine repeat disorders; monoclonal antibodies and multi-specific fusion proteins for targeted immuno-oncology applications; anti-ROR1 therapeutic antibodies designed to induce antibody-dependent cellular cytotoxicity against solid and hematological tumors; and dual-mechanism biologics targeting immunosuppressive pathways, including the GARP-TGFβ1 complex, to reactivate antitumor immune responses. Founded in 2010 and headquartered in Wrocław, Poland, MultiQure conducts its scientific research and clinical development in Poland while targeting global biopharmaceutical markets through clinical collaborations and out-licensing partnerships. In recent corporate developments, the company executed a strategic business model transformation, officially changing its corporate name from Pure Biologics S.A. to MultiQure S.A. to reflect its core focus on genetic medicines. As part of this transition, the company integrated the multiQure RNAi platform through a multi-stage transaction involving Dystrogen Gene Therapies Inc., supported by a strategic partnership and equity investment from Biofund Capital Management, which acquired a major shareholding and secured PLN 50 million in capital to accelerate clinical development toward regulatory filings. Furthermore, MultiQure streamlined its internal operations and oncology assets by entering into a commercial transaction to transfer the global development rights of its lead immuno-oncology molecules, PBA-0405 (PB004) and PBA-0111 (PB003G), to US-based Promittens Corporation.