Structure Therapeutics Inc.

Structure Therapeutics Inc.

GPCR
Structure Therapeutics Inc.US flagNASDAQ Global Market
47.34
USD
- -
- -
2.73BMarket Cap
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
- -
- -
- -
- -
Basic EPS, GAAP
-0.64
-1.72
-1.38
-2.44
-2.14
-1.99
-3.13
Free Cash Flow per Basic Share
-0.57
-1.31
-1.21
-2.22
-2.06
-3.19
-3.27
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-0.2
-0.56
-1
3.25
5.03
7.14
6.35
Tangible Book Value per Share
-0.2
-0.56
-1
3.25
5.03
7.14
6.35
Basic Weighted Avg Shares
25
25
38
37
57
71
69
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
- -
- -
Operating Margin (%)
- -
- -
- -
- -
- -
- -
- -
Depreciation Expense
- -
- -
- -
- -
1
1
2
Net Income, GAAP
-16
-40
-51
-90
-123
-141
-215
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
0.51
Profit Margin (%)
- -
- -
- -
- -
- -
- -
- -
Working Capital
35
101
80
449
855
1,507
1,306
LT Debt
- -
- -
- -
4
2
4
4
Total Equity
-22
-65
-115
453
865
1,516
1,354
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
-18.6
-11.86
-20.21

Capital Structure

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
ST Debt
3
3
3
LT Borrowings
- -
- -
- -
LT Finance Leases
4
3
4
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
213
213
213
Market Capitalization
14,780
10,277
11,443

Working Capital

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
Total Current Assets
1,570
1,491
1,372
Cash, Cash Equivalents & STI
1,446
1,459
1,343
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
63
57
66
Payables & Accruals
48
48
56
ST Debt
3
3
3
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
-12.23%
75.34%
Free Cash Flow
- -
76.87%
91.49%
Net Income, GAAP
- -
60.86%
15.24%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.56
-0.53
-0.59
-0.64
-2.14
2025
-0.82
-1.07
-1.12
0.47
-1.99
2026
-1.05
-1.46
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

CEO
Raymond C. Stevens
Full Time Employees
281
Sector
Healthcare
Industry
Biotechnology
Address
611 Gateway Boulevard South San Francisco CA United States of America 94080
IPO Date
Feb 3, 2023
Business
Structure Therapeutics Inc. (NASDAQ:GPCR) is a clinical-stage biopharmaceutical company that develops novel oral small molecule therapeutics targeting G-protein coupled receptors (GPCRs) for chronic diseases with unmet medical needs, including obesity, type 2 diabetes, pulmonary fibrosis, and cardiopulmonary conditions; its lead candidate, aleniglipron (GSBR-1290), is an oral glucagon-like peptide-1 receptor (GLP-1R) agonist in Phase 2b trials (ACCESS and ACCESS II) for obesity and overweight with topline data expected by year-end 2025; additional pipeline assets include ACCG-2671 and ACCG-3535, oral amylin receptor agonists in IND-enabling studies and preclinical development for obesity with Phase 1 initiation planned by late 2025, ANPA-0073, an oral apelin receptor (APJR) agonist phase 2-ready for muscle-sparing weight loss, LTSE-2578, a lysophosphatidic acid 1 receptor (LPA1R) antagonist that completed Phase 1 for idiopathic pulmonary fibrosis, discovery programs modulating glucose-dependent insulinotropic polypeptide receptor (GIPR) with agonist, dual GLP-1R/GIPR agonist and antagonist candidates for obesity, and glucagon receptor (GCGR) program with agonist and dual GLP-1R/GCGR agonist hits; the company leverages structure-based drug discovery, computational chemistry, and structural biology platforms to optimize binding and pharmacokinetics for metabolic, inflammatory, and cardiopulmonary disorders. Founded in 2016 and formerly known as ShouTi Inc., Structure Therapeutics is headquartered in South San Francisco, California, with operations in the United States and China targeting global patient populations. Recent developments include completion of enrollment in aleniglipron Phase 2b obesity studies, announcement of three additional aleniglipron clinical studies for competitive positioning, advancement of oral amylin programs, asset sale of a program to Exelixis generating $10 million upfront with $5.2 million received, $547 million in financing secured in 2024, and a strengthened cash position of $883.5 million as of year-end 2024 funding operations through 2027.

Company News

  • Structure Therapeutics to Participate in Upcoming Healthcare Investor Conferences

  • Septerna: GPCR Programs May Be Experimental, But I'm Holding For The Long Term

  • NVO vs. GPCR: Which Obesity Stock Is the Better Buy Right Now?

  • Structure Therapeutics: A Strong Bet For An Oral GLP-1 Approval Before 2030

  • LLY Up Around 6% Post Robust Q2 Results: Buy, Sell or Hold the Stock?

  • AbCellera Announces Positive Top-Line Phase 2 Clinical Trial Results for ABCL635, Demonstrating Significant Reduction in Frequency and Severity of Vasomotor Symptoms and a Favorable Tolerability Profi

  • The Next Phase Of The Obesity Drug Race

  • Structure Therapeutics: My Top Small-Cap Pick For The Obesity Market (Upgrade)

  • Structure Therapeutics Inc. (GPCR) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript

  • Structure's experimental obesity pill shows no signs of liver injury

  • Structure Therapeutics Announces Publication in Nature Medicine Highlighting Phase 2b ACCESS Program of Aleniglipron for Obesity

  • Structure Therapeutics Announces Participation in Upcoming Investor Conferences

  • If Viking Therapeutics Is Acquired, Here’s Who Wins

  • This Biotech Is Up 60%. A Top Healthcare Fund Just Bought Another $11 Million

  • Can Mounjaro, Zepbound & Foundayo Keep Fueling LLY's Growth Story?

  • Monashee Scales Back Its Bet on Structure Therapeutics

  • This Obesity Drug Stock Has Jumped 60% as Phase 3 Plans Advance. A Fund Just Sold $4.7 Million

  • Can Novo Nordisk Sustain Its GLP-1 Edge Amid Lilly's Growing Pressure?

  • Lilly Bets on Next-Generation Obesity Drugs to Stay Ahead

  • Nxera Pharma Announces Progress of Out-Licensing of GPCR-targeted Program and Participation in Series A Financing