- CEO
- Wei Cheng Guo
- Full Time Employees
- 2,843
- Sector
- Health technology
- Industry
- Pharmaceuticals: other
- Address
- Office Tower, Convention Plaza Beijing China
- IPO Date
- Oct 28, 2010
- Business
- Sihuan Pharmaceutical Holdings Group Ltd. (0460.HK) is an investment holding company engaged in the research, development, manufacture, and sale of pharmaceutical products with a focus on cardio-cerebral vascular, central nervous system, metabolism, oncology, diabetes, and anti-infectives therapeutic areas; it also operates in medical aesthetics and innovative biopharmaceuticals. Founded in 2001 and headquartered in Wan Chai, Hong Kong, the company maintains integrated production, R&D, and marketing capabilities supported by approximately 600 R&D personnel and an extensive nationwide distribution network in China. Its core products encompass branded generics and innovative drugs such as cinepazet maleate injection (Kelinao) for acute ischemic stroke, cardio-cerebral vascular treatments including stroke product lines, oncology drugs like CDK4/6 inhibitors in clinical trials, metabolism and diabetes therapies including metformin hydrochloride tablets that passed consistency evaluation, central nervous system offerings like gabapentin capsules, anti-infectives such as azithromycin and plazomicin, and medical aesthetics products under Meiyan Space featuring over 40 items including botulinum toxin Letybo and hyaluronic acid Persnica; the pipeline includes more than 60 innovative biopharmaceuticals and generic pharmaceuticals across small molecule, large molecule, monoclonal antibodies, bispecific antibodies, and ADCs targeting oncology, digestive diseases, and NASH. In recent developments, subsidiaries acquired additional equity stakes totaling approximately 6.99% in Xuanzhu Biopharm for RMB596 million between October and November 2024 to bolster control ahead of a proposed spin-off and Main Board listing on the Hong Kong Stock Exchange; the company signed a global cooperation agreement with U.S.-based Abalone Bio in October 2025 for a new-generation GPCR-targeted innovative therapy for weight loss and muscle gain, building on an earlier strategic investment; it completed strategic funding in Suisselle SA in September 2025 and advanced partnerships such as with South Korea's Cellontech for collagen injectables, while securing NMPA approvals for 13 generic products including dopamine hydrochloride injection in 2024 and initiating Phase II trials for pirotinib. The group primarily serves the Chinese prescription drug market with expansion into international R&D collaborations and operates through subsidiaries like Hainan Sihuan and Xuanzhu Biopharm, emphasizing a two-wheel drive strategy in medical aesthetics and biopharmaceuticals.