MacroGenics, Inc.
NASDAQ Global SelectCapital Structure
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in mil. unless spec.Working Capital
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in mil. unless spec.Growth Rates
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in mil. unless spec.Quarterly Revenue
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in mil. unless spec.Quarterly Earnings Per Share
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in mil. unless spec.Quarterly Dividends Per Share
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in mil. unless spec.- CEO
- Eric Blasius Risser
- Full Time Employees
- 341
- Sector
- Healthcare
- Industry
- Biotechnology
- Address
- 9704 Medical Center Drive Rockville MD United States of America 20850
- IPO Date
- Oct 10, 2013
- CIK
- 0001125345
- Website
- macrogenics.com
- Similar Companies
- Business
- MacroGenics, Inc. (NASDAQ: MGNX) is a clinical-stage biopharmaceutical company that discovers, develops, manufactures, and commercializes innovative monoclonal antibody-based therapeutics for cancer treatment; its proprietary platforms include DART molecules, antibody-drug conjugates (ADCs), and Fc-optimized monoclonal antibodies (mAbs). The company, founded in 2000 and headquartered in Rockville, Maryland, focuses on oncology indications such as metastatic castration-resistant prostate cancer (mCRPC), prostate cancer (PROC), colorectal cancer with gynecologic origins (CCGC), and multiple solid tumors, with operations primarily in the United States and partnerships extending globally. Core wholly-owned pipeline candidates comprise lorigerlimab (PD-1 x CTLA-4 DART) in Phase 3 for mCRPC (LORIKEET study) and Phase 2 for PROC/CCGC (LINNET study); MGC026 (B7-H3 ADC), MGC028 (ADAM9 ADC), and MGC030 (undisclosed ADC), all in Phase 1 for solid tumors; partnered programs include MARGENZA (HER2 Fc-optimized mAb, global rights sold to TerSera Therapeutics LLC for $40 million upfront plus up to $35 million milestones), ZYNYZ (PD-1 mAb partnered with Incyte, supplemental BLA anticipated 2H2025 for squamous cell anal carcinoma), TZIELD (CD3 mAb partnered with Sanofi, regulatory decisions expected 2H2025 for type 1 diabetes), MGD024 (CD123 x CD3 DART under Gilead option, up to $1.7 billion potential), and undisclosed DART/TRIDENT bispecifics. Recent developments include a $70 million upfront royalty purchase agreement with Sagard Healthcare Partners for ZYNYZ in Q2 2025, appointment of Eric Risser as President and CEO outlining 2025-2026 priorities for pipeline advancement and capital efficiency, sale of MARGENZA rights to TerSera with an $8 million amendment fee to the prior partner in 4Q2024 and ongoing drug substance manufacturing, IND submission for MGC028 by end-2024 with Phase 1 initiation in 2025, and cash position of $176.5 million as of June 30, 2025, extending into H1 2027.
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