OnKure Therapeutics, Inc.

OnKure Therapeutics, Inc.

OKUR
OnKure Therapeutics, Inc.US flagNASDAQ Global Market
4.16
USD
-0.06
- -
56.91MMarket Cap
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
- -
- -
Basic EPS, GAAP
-2.21
-2.65
-15.28
- -
-4.33
Free Cash Flow per Basic Share
-2.11
-2.61
-14.84
- -
-3.74
Dividend per Share
- -
- -
- -
- -
- -
Book Value per Share
-4.28
-7.65
-44.89
- -
-16.89
Tangible Book Value per Share
-4.08
-7.63
30.12
- -
13.58
Basic Weighted Avg Shares
13
13
3
- -
14
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
Operating Margin (%)
- -
- -
- -
- -
- -
Depreciation Expense
- -
1
1
1
1
Net Income, GAAP
-30
-35
-53
-60
-59
Effective Tax Rate (%)
- -
- -
- -
- -
- -
Profit Margin (%)
- -
- -
- -
- -
- -
Working Capital
8
26
102
55
183
LT Debt
- -
- -
1
- -
- -
Total Equity
-54
-102
104
56
184
Return on Invested Capital (%)
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
1
1
- -
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
14
14
41
Market Capitalization
37
39
56

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
72
61
197
Cash, Cash Equivalents & STI
70
59
192
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
6
6
14
Payables & Accruals
3
3
13
ST Debt
1
1
- -
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
- -
-45.89%
Free Cash Flow
- -
- -
1.38%
Net Income, GAAP
- -
- -
12.99%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.71
-1.06
-0.87
-2.76
-15.28
2025
-1.19
-1.14
-1.09
-0.99
- -
2026
-1.11
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Nicholas A. Saccomano
Full Time Employees
46
Sector
Healthcare
Industry
Biotechnology
Address
6707 Winchester Circle Boulder CO United States of America 80301
IPO Date
Apr 8, 2021
Business
OnKure Therapeutics, Inc. (Nasdaq: OKUR) is a clinical-stage biopharmaceutical company focused on the discovery and development of best-in-class precision medicines targeting biologically validated drivers of cancer underserved by available therapies, particularly oncogenic mutations in phosphoinositide 3-kinase alpha (PI3Kα); its lead product candidate is OKI-219, a selective PI3Kα H1047R mutant inhibitor in Phase 1 PIKture-01 trial for advanced solid tumors including breast cancer, with dose escalation completed and triplet combination arms enrolling; the pipeline also includes a PI3Kα PAN mutant selective inhibitor program at candidate selection and a PI3Kα E542K/E545K mutant selective inhibitor program in active discovery, all targeting breast cancer and solid tumors. Founded in 2011 and headquartered in Boulder, Colorado, the company employs a structure-based drug design platform to optimize tolerability and efficacy across its oncology portfolio. In October 2024, OnKure completed a merger with Reneo Pharmaceuticals, Inc. and a concurrent $65 million private placement with investors including Acorn Bioventures, Cormorant Asset Management, Deep Track Capital, Perceptive Advisors, Samsara BioCapital, Surveyor Capital, and Vestal Point Capital, providing a cash runway into Q4 2026 to support multiple clinical readouts.

Company News

APIChat
  • OnKure Therapeutics Reports First Quarter 2026 Financial Results

  • OnKure Therapeutics Announces Oversubscribed $150 Million Private Placement to Advance Next-Generation PI3Kα Pan-Mutant Selective Inhibitor Candidates in Breast Cancer and Vascular Anomalies

  • OnKure Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results

  • OnKure Therapeutics, Inc. (NASDAQ:OKUR) Given Consensus Rating of “Hold” by Analysts

  • OnKure Therapeutics Reports Third Quarter 2025 Financial Results and Provides a Business Update

  • OnKure Therapeutics to Participate in Upcoming Investor Conferences

  • OnKure Therapeutics Reports Second Quarter 2025 Financial Results and Provides a Business Update

  • OnKure Therapeutics Reports First Quarter 2025 Financial Results and Business Highlights

  • OnKure Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Business Highlights

  • OnKure Therapeutics to Present at Upcoming Leerink and Stifel Investor Conferences

  • OnKure Announces Encouraging Preliminary Safety, Tolerability, and Pharmacokinetic (PK) Data from its First-In-Human PIKture-01 Trial of OKI-219

  • OnKure Announces New Date for Upcoming Investor Call

  • OnKure to Present Clinical and Preclinical Data for OKI-219 at the 2024 San Antonio Breast Cancer Symposium

  • OnKure: Looking To Alter PI3K Inhibitor Targeting In Breast Cancer And Beyond

  • OnKure Announces Closing of Merger with Reneo Pharmaceuticals and Concurrent Private Placement of $65 Million