XtalPi Holdings Limited

XtalPi Holdings Limited

0.74
USD
-0.16
(-17.34%)
5.22BMarket Cap
Apr 01Next Earn
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
0.02
0.04
0.05
0.14
0.21
- -
Basic EPS, GAAP
-0.63
-0.42
-0.56
-0.79
0.03
- -
Free Cash Flow per Basic Share
-0.12
-0.18
-0.2
-0.28
-0.06
- -
Dividend per Share
- -
- -
- -
- -
- -
- -
Book Value per Share
-1.06
-1.56
-2.13
1.16
2.18
2.18
Tangible Book Value per Share
-1.06
-1.57
-2.14
1.16
2.13
2.13
Basic Weighted Avg Shares
3,407
3,407
3,407
1,929
3,782
3,911
Sales/Revenue/Turnover
63
133
174
266
803
- -
Operating Margin (%)
-534.47
-387.19
-437.67
-269.4
-56.09
- -
Depreciation Expense
23
69
122
139
116
- -
Net Income, GAAP
-2,137
-1,439
-1,914
-1,517
124
- -
Effective Tax Rate (%)
- -
- -
- -
- -
0.58
- -
Profit Margin (%)
-3,403.38
-1,078.72
-1,097.57
-569.23
15.42
- -
Working Capital
3,759
3,399
2,648
3,036
6,961
6,961
LT Debt
93
69
137
65
246
246
Total Equity
-3,604
-5,310
-7,241
3,992
9,431
9,431
Return on Invested Capital (%)
- -
- -
- -
- -
0.78
- -
Return on Capital (%)
- -
- -
- -
- -
1.74
- -
Return on Common Equity (%)
- -
- -
- -
- -
1.85
- -

Capital Structure

CNY

•

in mil. unless spec.
Dec'24
Jun'25
Dec'25
ST Debt
84
306
196
LT Borrowings
- -
7
175
LT Finance Leases
65
53
71
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
3,414
4,020
4,303
Market Capitalization
- -
19,327
36,476

Working Capital

CNY

•

in mil. unless spec.
Dec'24
Jun'25
Dec'25
Total Current Assets
3,315
5,969
7,467
Cash, Cash Equivalents & STI
3,101
5,305
7,051
Accounts Receivable, Net
91
494
148
Inventories
- -
27
95
Total Current Liabilities
280
616
506
Payables & Accruals
- -
- -
- -
ST Debt
84
306
196
Deferred Revenue
- -
- -
- -

Growth Rates

CNY

•

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
- -
136.23%
Free Cash Flow
- -
- -
-55.02%
Net Income, GAAP
- -
- -
-108.16%
Sales/Revenue/Turnover
- -
- -
201.25%
Total Cash Common Dividend
- -
- -
- -

Semi-annual Revenue

CNY

•

in mil. unless spec.

Year

H1
H2
FY
2023
- -
- -
174
2024
- -
- -
266
2025
- -
- -
803

Semi-annual Earnings Per Share

CNY

•

in mil. unless spec.

Year

H1
H2
FY
2023
- -
- -
-0.56
2024
- -
- -
-0.79
2025
- -
- -
0.03

Semi-annual Dividends Per Share

CNY

•

in mil. unless spec.

Year

H1
H2
FY
2023
- -
- -
- -
2024
- -
- -
- -
2025
- -
- -
- -

Company Description

CEO
Jian Ma
Full Time Employees
1,254
Sector
Health technology
Industry
Biotechnology
Address
Second Phase of the International Shenzhen GD China 518000
IPO Date
Jul 7, 2024
Website
xtalpi.com
Business
XtalPi Holdings Ltd (2228.HK), formerly QuantumPharm Inc, is a holding company that develops and provides quantum physics-based, artificial intelligence-powered, and robotics-driven technology platforms for drug discovery, material science research and development solutions, and intelligent laboratory automation services in Mainland China, the United States, Europe, South Korea, Japan, and internationally; its core offerings include XMolGen, an AI small molecule drug discovery computation platform; XtalFold, an antibody-antigen complex structure prediction platform; Xtalgazer, a drug crystallization research and development platform leveraging physical models and AI algorithms for physicochemical properties, crystal structure, and stability predictions; PatSight, an AI-powered patent data extraction tool; XFEP, a tool for affinity predictions between compounds and biological targets; automated chemical synthesis services; discovery chemistry solutions such as hit-to-lead optimization and focused library services; solid-state research encompassing crystal structure determination; AI+robotics laboratory automation solutions featuring modular robots like the NeoDispenser gripper; digital chemistry platforms for patent data extraction and novel chemical space exploration; and PepiX, a peptide and protein R&D platform integrating generative AI design, automated synthesis, trillion-scale libraries, and high-throughput screening; the company was founded in 2015 and is headquartered in Shenzhen, China. Recent developments include the launch of the PepiX platform with preclinical immunogenicity results in cancer vaccine candidates advancing toward clinical trials; strategic partnerships such as a multi-billion dollar collaboration with Professor Gregory Verdine involving up to $5.89 billion in milestone payments; expanded agreements with Pfizer for molecular modeling and simulations; deals with Roche for robotics integration in high-throughput storage and retrieval systems; multi-million dollar arrangements with JW Pharmaceutical for automated synthesis and optimization in oncology and metabolic diseases; a partnership with Liangzhu Laboratory to establish a robotics-powered biomaterials facility; a letter of intent with Baicheng Medicine for AI-driven drug discovery in pain, narcolepsy, oncology, autoimmune diseases, and ophthalmology; and collaborations with DoveTree Medicines and PL Bioscience for pharmaceutical R&D.

Company News

  • XtalPi Holdings Limited to Announce 2026 Interim Results on August 19, 2026

  • XtalPi Receives Second Payment from DoveTree; First Oncology Asset Advances into IND-Enabling Studies