Protagenic Therapeutics, Inc.

Protagenic Therapeutics, Inc.

PTIX
Protagenic Therapeutics, Inc.US flagNASDAQ Capital Market
0.50
USD
+0.00
- -
905,104.00Market Cap
2010 Y
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
TTM
Revenue per Share
5,718,000
52.31
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Basic EPS, GAAP
-2,818,142.86
-632
-2,325.43
-1,025.86
-24.02
-12.33
-13.96
-9.56
-13.8
-17.18
-11.53
-16.11
-15.79
-2.58
Free Cash Flow per Basic Share
-1,607,142.86
-199.38
-1,704.74
-814.66
-12.04
-7.53
-5.85
-2.66
-7.31
-10.63
-6.47
-12.42
-12.05
-2.07
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-23,996,571.43
-119,708.31
-2,325.43
-3,351.29
-90.57
-59.16
-73.12
-82.67
-95.86
-84.42
-83.58
-99.18
-103.72
-4.55
Tangible Book Value per Share
727,000
-10,600.62
-161.64
-1,241.38
26.14
6.65
-1.15
-3.46
-6.23
37.77
22.43
11.82
2.89
-2.24
Basic Weighted Avg Shares
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
2
Sales/Revenue/Turnover
40
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Operating Margin (%)
-43.58
-791.76
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Depreciation Expense
2
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Net Income, GAAP
-20
-1
-1
- -
-2
-2
-3
-2
-3
-5
-4
-5
-6
-5
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
-49.29
-1,208.24
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Working Capital
2
-17
- -
- -
2
1
- -
- -
- -
10
7
4
1
-5
LT Debt
- -
- -
- -
1
- -
- -
- -
- -
1
- -
- -
- -
- -
- -
Total Equity
8
-17
- -
-1
2
1
- -
-1
-1
10
7
4
1
-2
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
22.78
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Jun'25
Sep'25
Dec'25
ST Debt
4
4
4
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
2
2
2
Market Capitalization
6
7
3

Working Capital

FRC

in mil. unless spec.
Jun'25
Sep'25
Dec'25
Total Current Assets
4
3
2
Cash, Cash Equivalents & STI
4
3
2
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
10
10
7
Payables & Accruals
3
2
2
ST Debt
4
4
4
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
-81.86%
-206.65%
-72.38%
Free Cash Flow
45.14%
71.54%
9.42%
Net Income, GAAP
45.59%
30.56%
10.5%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2023
- -
- -
- -
- -
- -
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2023
-2.33
-3.91
-4.51
- -
-16.11
2024
-5.44
-5.06
-1.98
- -
-15.79
2025
-2.75
-1.37
-0.47
1.14
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2023
- -
- -
- -
- -
- -
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Garo H. Armen
Full Time Employees
1
Sector
Healthcare
Industry
Biotechnology
Address
149 Fifth Avenue New York City NY United States of America 10010
IPO Date
Apr 27, 2021
Business
Protagenic Therapeutics, Inc. (Nasdaq: PTIX) is a biopharmaceutical company focused on the discovery, development, and commercialization of therapeutics targeting stress-related neuropsychiatric disorders, central nervous system conditions, epilepsy, obesity, and metabolic disorders. The company offers a diversified pipeline of peptide-based and cannabinoid therapeutics, including its lead clinical-stage asset PT-00114, a synthetic teneurin carboxy-terminal associated peptide (TCAP) in Phase I/IIa targeting post-traumatic stress disorder, treatment-resistant depression, generalized anxiety disorder, and substance use disorders via the biologics license application pathway; PHYX-001, a preclinical potassium channel modulator; multiple cannabinoid-based compounds with composition-of-matter intellectual property for central nervous system and cardiometabolic indications, including a proprietary obesity and metabolic dysfunction candidate competing with GLP-1 agonists; and modified stilbenoid compounds demonstrating preclinical anticonvulsant activity. Protagenic Therapeutics operates primarily in the United States with preclinical and early clinical programs addressing large unmet needs in neuropsychiatry and neurology. Founded in 1994 and headquartered in New York, New York, the company completed a transformative business combination with Phytanix Bio Inc. on May 19, 2025, expanding its pipeline from a single asset to six complementary drug candidates and integrating cannabinoid development expertise from former GW Pharmaceuticals team members experienced with Epidiolex and Sativex; subsequent warrant exchanges raised $3.1 million in May 2025 to fund pipeline advancement; and a 1-for-14 reverse stock split occurred on May 5, 2025.

Company News

APIChat
  • Protagenic Therapeutics Engages Floyd Regulatory Strategic Consulting as Regulatory Affairs Advisor and Danforth Health as Strategic Operations Partner

  • Protagenic Therapeutics Appoints Industry Veteran Bill Nichols Jr. as President to Accelerate Advancement of First-in-Class TCAP Pathway Therapy PT00114

  • Contrasting Vanda Pharmaceuticals (NASDAQ:VNDA) and Atrinsic (NASDAQ:PTIX)

  • Protagenic Therapeutics Completes Phytanix Separation, Strengthens Balance Sheet and Repositions the Company Around PT00114

  • Protagenic Therapeutics Upgrades from OTC Pink to OTCQB Venture Market

  • Atrinsic (NASDAQ:PTIX) Shares Up 10.9% – Should You Buy?

  • Head-To-Head Contrast: Praxis Precision Medicines (NASDAQ:PRAX) versus Atrinsic (NASDAQ:PTIX)

  • Results from Phase 1 Multiple-Dose Study of PT00114

  • Protagenic Therapeutics Announces Receipt of Nasdaq Non-Compliance Notice

  • Atrinsic (NASDAQ:PTIX) Trading Up 2.5% – Time to Buy?

  • Protagenic Therapeutics Announces Completion of Enrollment and Dosing in Phase 1 MAD Study

  • Protagenic Therapeutics Provides Update on Form 10-Q Filing Timeline and Nasdaq Compliance

  • Protagenic Therapeutics Advances PT00114 into Multiple-Dose Phase 1 Trial; Positioning for Phase 2 in Stress & Mood Disorders

  • Protagenic Therapeutics Announces Grant of new patent in Japan for its Modified Stilbenoid Program Drug Candidates

  • Protagenic Therapeutics Announces Grant of new patent in Japan for its Modified Stilbenoid Program Drug Candidates

  • Protagenic Therapeutics Receives $3.1 Million from Recent Warrant Activity

  • Gold Gains Over 1%; Protagenic Therapeutics Shares Spike Higher

  • PTIX Stock Alert: Halper Sadeh LLC Is Investigating Whether the Merger of Protagenic Therapeutics, Inc. Is Fair to Shareholders

  • Protagenic Therapeutics and Phytanix Announce Business Combination to form Neuroactive Biopharmaceutical Company with Six Drug Candidates in Development including Treatments for Obesity and Metabolic Disorders

  • Protagenic Therapeutics to Effect 1-for-14 Reverse Stock Split