Sionna Therapeutics, Inc.

Sionna Therapeutics, Inc.

SION
Sionna Therapeutics, Inc.US flagNASDAQ Global Market
36.70
USD
+0.22
- -
1.66BMarket Cap
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
- -
- -
Basic EPS, GAAP
-2.32
-1.7
-1.45
- -
-1.92
Free Cash Flow per Basic Share
-2.19
-1.61
-1.24
- -
-1.62
Dividend per Share
- -
- -
- -
- -
- -
Book Value per Share
-4.16
-4.3
-4.27
- -
-6.36
Tangible Book Value per Share
-12.63
-9.49
-3.86
- -
6.48
Basic Weighted Avg Shares
17
28
42
- -
44
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
Operating Margin (%)
- -
- -
- -
- -
- -
Depreciation Expense
- -
1
1
1
1
Net Income, GAAP
-40
-47
-62
-75
-86
Effective Tax Rate (%)
- -
- -
- -
- -
- -
Profit Margin (%)
- -
- -
- -
- -
- -
Working Capital
76
31
141
230
211
LT Debt
- -
10
9
7
7
Total Equity
-70
-115
-164
307
288
Return on Invested Capital (%)
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
1
1
1
LT Borrowings
- -
- -
- -
LT Finance Leases
8
7
7
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
44
45
45
Market Capitalization
1,157
1,642
1,783

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
252
241
221
Cash, Cash Equivalents & STI
248
236
216
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
10
12
10
Payables & Accruals
5
6
7
ST Debt
1
1
1
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
- -
-287.42%
Free Cash Flow
- -
- -
26.24%
Net Income, GAAP
- -
- -
22.01%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.43
-0.2
- -
-0.37
-1.45
2025
-0.62
-0.41
-0.46
-0.46
- -
2026
-0.6
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Michael Cloonan
Full Time Employees
41
Sector
Healthcare
Industry
Biotechnology
Address
21 Hickory Drive Suite 500 Waltham MA United States of America 02451
IPO Date
Feb 7, 2025
Business
Sionna Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing precision medicines for diseases caused by dysregulation of RNA. The company’s core products and services include the discovery and development of small molecule and RNA-targeted therapeutics designed to modulate RNA splicing and improve gene expression. Sionna Therapeutics utilizes proprietary RNA-targeting platforms to create treatments for genetically defined patient populations, primarily in the areas of neurology, ophthalmology, and other rare diseases. The company operates primarily in the United States and internationally as it advances its pipeline through clinical trials. Founded in 2018, Sionna Therapeutics is headquartered in Cambridge, Massachusetts. Recent major company developments include strategic collaborations and advancements in its drug pipeline with a focus on moving lead candidates into clinical stages. Sionna has also expanded its research capabilities through partnerships and has progressed new product candidates into early clinical trials within the last one to two years. These steps emphasize Sionna’s commitment to translating its platform technology into novel therapeutic candidates addressing unmet medical needs in precision RNA medicine. The company continues to broaden its presence in biopharmaceutical innovation through strategic alliances and operational growth consistent with its mission to develop RNA-targeted therapies. Sionna Therapeutics operates within the biotechnology and pharmaceutical industry segments, targeting patients with rare and serious diseases caused by RNA splicing errors. Its customer base includes research institutions, healthcare providers, and ultimately patients requiring advanced precision medical treatments. It functions independently and may engage in collaborations with larger pharmaceutical firms to leverage its RNA-focused technologies. The company’s geographic footprint spans the US and global markets through clinical development and research partnerships.

Company News

APIChat
  • Sionna Therapeutics to Participate in Upcoming June 2026 Investor Conferences

  • Sionna Therapeutics to Participate in the 2026 RBC Capital Markets Global Healthcare Conference

  • First Look: eBay rebuffs GME, oil swings, CEOs to China

  • Sionna Therapeutics Reports First Quarter 2026 Financial Results

  • Sionna Therapeutics Completes Enrollment in PreciSION CF Phase 2a Trial Evaluating NBD1 Stabilizer, SION-719, Added to Standard of Care in Participants with Cystic Fibrosis

  • Insider Selling: Sionna Therapeutics (NASDAQ:SION) Director Sells $2,128,201.14 in Stock

  • Sionna Therapeutics (NASDAQ:SION) Director Sells $2,128,201.14 in Stock

  • Sionna Therapeutics (NASDAQ:SION) Director Sells $10,287,918.04 in Stock

  • Insider Selling: Sionna Therapeutics (NASDAQ:SION) Director Sells $10,528,924.32 in Stock

  • Insider Selling: Sionna Therapeutics (NASDAQ:SION) Director Sells $10,287,918.04 in Stock

  • Insider Selling: Sionna Therapeutics (NASDAQ:SION) Director Sells $10,528,924.32 in Stock

  • Sionna Therapeutics to Participate in the Raymond James 2026 Biotech Innovation Symposium

  • Sionna Chief Legal Officer Cashed Out Her Shares. Her Options Are Another Story

  • Sionna Stock Is Up 144% This Past Year. Is the Biotech a Buy as One Fund Makes a $7 Million Bet?

  • This Investor Sold $5 Million of a Biotech Stock Up 118% in a Year, but Here's Why It Still Seems Bullish on Shares

  • Sionna Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results

  • Sionna Therapeutics to Participate in Upcoming March 2026 Investor Conferences

  • Orbimed Advisors Llc Sells 29,063 Shares of Sionna Therapeutics (NASDAQ:SION) Stock

  • Peter Thompson Sells 29,063 Shares of Sionna Therapeutics (NASDAQ:SION) Stock

  • Sionna Therapeutics to Present at the Guggenheim Securities Emerging Outlook: Biotech Summit 2026