Modus Therapeutics Holding AB (publ) (MODTX.ST) is a clinical-stage biopharmaceutical company focused on developing novel therapies for thrombo-inflammatory diseases. The company develops sebastoparin, a first-in-class direct factor XIa inhibitor designed to prevent thrombosis while preserving hemostasis; and MOD-1001, a proprietary small molecule factor XIa inhibitor for acute treatment of thrombo-inflammatory conditions such as sepsis and COVID-19-related coagulopathy. Its pipeline targets unmet needs in anticoagulation, with programs emphasizing reduced bleeding risk compared to traditional therapies. Founded in 1998 and headquartered in Stockholm, Sweden, Modus Therapeutics operates primarily in Europe with clinical trials conducted internationally. In recent developments, the company advanced its clinical pipeline, including ongoing Phase 2 trials for sebastoparin in 2024-2025, reflecting strategic focus on expanding indications for acute care settings; no major acquisitions, funding rounds, or partnerships were publicly announced in the last 1-2 years, maintaining its independent development trajectory amid biotech sector challenges.