Peptidream Inc.

Peptidream Inc.

1,072.50
JPY
-12.00
(-1.11%)
136.86BMarket Cap
Nov 11Next Earn
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
7.64
22.62
38.94
42.84
53.26
58.41
- -
92.92
73.09
206.83
221.37
360.14
143.21
- -
Basic EPS, GAAP
1.39
9.18
14.23
16.54
19.35
22.42
- -
35.4
19.96
58.19
23.41
115.85
-28.99
- -
Free Cash Flow per Basic Share
-0.01
1.35
-3.92
-3.53
-12.01
34.69
- -
9.12
42.2
-31.26
85.21
166.86
-116.23
- -
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
54.56
62.6
90.74
106.41
120
139.41
135.65
168.77
195.26
246.79
311.32
437.94
398.78
377.66
Tangible Book Value per Share
54.56
62.57
89.8
105.35
119.05
138.47
134.72
168.14
194.68
165.12
229.67
356.82
318.39
297.35
Basic Weighted Avg Shares
107
109
111
114
121
124
125
126
129
130
130
130
129
129
Sales/Revenue/Turnover
819
2,474
4,328
4,896
6,427
7,217
- -
11,677
9,422
26,852
28,712
46,677
18,521
- -
Operating Margin (%)
24.59
56.22
58.88
50.87
45.29
49.6
- -
59.87
43.16
33.44
23.59
45.23
-27.07
- -
Depreciation Expense
74
103
143
195
513
521
- -
571
633
1,973
2,433
2,248
2,127
- -
Net Income, GAAP
149
1,004
1,581
1,891
2,335
2,770
- -
4,448
2,573
7,554
3,036
15,015
-3,749
- -
Effective Tax Rate (%)
33.1
32.76
33.16
27.95
25.91
27.23
- -
26.11
32.35
- -
30.27
28.12
- -
- -
Profit Margin (%)
18.14
40.58
36.54
38.62
36.34
38.39
- -
38.09
27.31
28.13
10.57
32.17
-20.24
- -
Working Capital
5,699
5,538
6,901
7,174
6,345
7,931
7,361
10,935
12,460
14,042
18,608
38,803
15,501
25,100
LT Debt
- -
- -
- -
- -
- -
- -
- -
- -
- -
18,358
19,634
17,042
- -
13,076
Total Equity
5,863
6,912
10,243
12,181
14,709
17,449
16,978
21,217
25,350
32,041
40,350
56,762
51,528
48,555
Return on Invested Capital (%)
2.31
14.06
18.52
15.33
15.53
15.52
- -
25.88
11.39
- -
7.94
20.51
- -
- -
Return on Capital (%)
2.57
15.72
18.44
16.86
17.37
17.23
- -
23.29
11.05
- -
7.97
22.29
- -
- -
Return on Common Equity (%)
2.57
15.72
18.44
16.86
17.37
17.23
- -
23.29
11.05
26.33
8.39
30.92
-6.92
- -

Capital Structure

JPY

•

in mil. unless spec.
Jun'24
Mar'26
Jun'26
ST Debt
2,590
- -
2,613
LT Borrowings
18,339
- -
13,076
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
130
128
129
Market Capitalization
322,863
153,870
136,860

Working Capital

JPY

•

in mil. unless spec.
Jun'24
Mar'26
Jun'26
Total Current Assets
61,782
- -
33,073
Cash, Cash Equivalents & STI
25,484
- -
23,609
Accounts Receivable, Net
32,766
- -
4,497
Inventories
2,790
- -
3,677
Total Current Liabilities
18,250
- -
7,973
Payables & Accruals
- -
- -
- -
ST Debt
2,590
- -
2,613
Deferred Revenue
- -
- -
- -

Growth Rates

JPY

•

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
18.38%
20.65%
-9.22%
Free Cash Flow
- -
-49.25%
-169.51%
Net Income, GAAP
- -
72.25%
-124.97%
Sales/Revenue/Turnover
- -
34.97%
-60.32%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

JPY

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
4,225
31,908
- -
- -
46,677
2025
- -
- -
- -
- -
18,521
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

JPY

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-6.5
144.8
- -
- -
115.85
2025
- -
- -
- -
- -
-28.99
2026
- -
- -
- -
- -
- -

Quarterly Dividends Per Share

JPY

•

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

CEO
Patrick Crawford Reid
Full Time Employees
645
Sector
Health technology
Industry
Biotechnology
Address
3-25-23 Tonomachi Kawasaki KN Japan 210-0821
IPO Date
Jun 11, 2013
Business
PeptiDream Inc. (4587.T), a public biopharmaceutical company founded in 2006 and headquartered in Kawasaki, Japan, engages in the discovery, development and commercialization of constrained peptides, small molecules and peptide-drug conjugate therapeutics; macrocyclic peptide-based therapeutics and diagnostics; peptide-drug conjugates including radioligand therapies and multi-functional peptide conjugates; and radiopharmaceutical and radio-diagnostic products. The company leverages its proprietary Peptide Discovery Platform System (PDPS) to generate non-standard peptide libraries for identifying potent, selective macrocyclic peptide candidates targeting oncology, immunology, metabolic disorders, neuromuscular conditions, infectious diseases and allergic indications, with a development pipeline featuring PD-L1 (Ph1), PD-L1 BMS-986229 (Ph1), CD38 BHV-1100 + NK cells for multiple myeloma (Ph1), GhR AZP-3813 for acromegaly/NET (Ph1), preclinical programs including Glypican-3 for liver cancer, Myostatin for DMD/muscle disorders, TfR for neuromuscular disorders, c-Kit for allergic conditions, c-Met and HA-protein for influenza. PeptiDream operates primarily through its Drug Discovery and Development segment via strategic research collaborations, technology licensing of PDPS and pipeline expansion with global pharmaceutical partners including Novartis, MSD (Merck), Genentech and Bristol Myers Squibb, serving therapeutic areas across oncology, central nervous system disorders and metabolic diseases with worldwide geographic reach. Recent developments include a 2024 expansion of its long-standing peptide discovery collaboration with Novartis granting exclusive global rights for radioligand therapy programs using PDPS-optimized macrocyclic peptides conjugated with radionuclides, featuring $180 million upfront payment and up to $2.7 billion in milestones plus royalties; ongoing multi-target partnerships such as with MSD for peptide drug conjugates; and pipeline advancements including multiple Phase 1 clinical programs.

Company News

  • PeptiDream (PPTDF) Expected to Announce Quarterly Earnings on Wednesday

  • PeptiDream Announces First Dosing of Claudin18.2 Targeting Radiopharmaceutical Candidate 64Cu-PD-29875 in Patients with Gastric Cancer

  • PeptiDream, PDRadiopharma and Curium Group Announce Completion of Patient Dosing in Clinical Trial of 64Cu-PSMA-I&T for Prostate Cancer in Japan

  • Curium Group, PeptiDream and PDRadiopharma Announce Completion of Patient Dosing in Clinical Trial of 64Cu-PSMA-I&T for Prostate Cancer in Japan

  • PeptiDream Announces the Initiation of Phase 1 Clinical Trial by Its Collaboration Partner

  • PeptiDream Inc. (PPTDF) Q4 2025 Earnings Call Transcript

  • Curium Group, PeptiDream and PDRadiopharma Enroll First Patient to Registrational Clinical Trial of Lu-PSMA-I&T for Prostate Cancer in Japan

  • PeptiDream Announces Promising Pre-Clinical Results of Proprietary Oral IL-17A and IL-17F Dual Inhibitor with Biologic-Like Efficacy for the Treatment of Psoriasis