Tyra Biosciences, Inc.

Tyra Biosciences, Inc.

TYRA
Tyra Biosciences, Inc.US flagNASDAQ Global Select
28.65
USD
+3.79
- -
1.71BMarket Cap
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
- -
- -
- -
- -
- -
- -
Basic EPS, GAAP
-0.4
-0.42
-1.91
-1.32
-1.62
-1.51
-2.01
-2.4
Free Cash Flow per Basic Share
-0.26
-0.36
-1.77
-1.21
-1.19
-1.23
-1.6
-1.78
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-0.13
-0.37
7.28
6.09
4.75
6.76
4.83
5.93
Tangible Book Value per Share
-0.13
-0.37
7.28
6.09
4.75
6.76
4.83
5.93
Basic Weighted Avg Shares
10
22
14
42
43
57
60
62
Sales/Revenue/Turnover
- -
- -
- -
- -
- -
- -
- -
- -
Operating Margin (%)
- -
- -
- -
- -
- -
- -
- -
- -
Depreciation Expense
- -
- -
- -
- -
- -
1
1
1
Net Income, GAAP
-4
-9
-26
-55
-69
-86
-120
-149
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
- -
- -
- -
- -
- -
- -
- -
- -
Working Capital
-5
13
300
252
196
333
247
342
LT Debt
- -
- -
1
2
6
6
5
5
Total Equity
-5
-14
302
258
204
343
259
354
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
-19.77
-29.92
-31.6
-39.83
-45.31

Capital Structure

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
ST Debt
- -
- -
1
LT Borrowings
- -
- -
- -
LT Finance Leases
5
5
5
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
54
59
60
Market Capitalization
1,412
2,278
1,906

Working Capital

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
Total Current Assets
265
395
367
Cash, Cash Equivalents & STI
256
383
354
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
18
19
25
Payables & Accruals
18
19
24
ST Debt
- -
- -
1
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
-460.85%
-24.47%
Free Cash Flow
- -
76.87%
35.27%
Net Income, GAAP
- -
76.16%
38.7%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.35
-0.32
-0.41
-0.43
-1.51
2025
-0.47
-0.47
-0.5
-0.57
-2.01
2026
-0.64
-0.69
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

CEO
Todd Harris
Full Time Employees
87
Sector
Healthcare
Industry
Biotechnology
Address
2656 State Street Carlsbad CA United States of America 92008
IPO Date
Sep 15, 2021
Website
tyra.bio
Business
Tyra Biosciences, Inc. is a clinical-stage biotechnology company focused on developing next-generation precision medicines targeting large opportunities in fibroblast growth factor receptor (FGFR) biology. Founded in 2018 and headquartered in Carlsbad, California, Tyra leverages its proprietary SNÅP platform for precision drug discovery aimed at overcoming acquired resistance to current cancer therapies. The company’s main products include TYRA-300, an oral selective FGFR3 inhibitor in Phase 2 development for treating FGFR3-positive solid tumors such as metastatic urothelial carcinoma and pediatric achondroplasia, TYRA-200, an oral FGFR1/2/3 inhibitor in clinical trials for FGFR2-driven intrahepatic cholangiocarcinoma and other advanced solid tumors, and TYRA-430, an oral FGFR4/3-biased inhibitor targeting FGF19+/FGFR4-driven cancers in ongoing clinical trials. Recent major developments include clearance by the U.S. FDA to proceed with a Phase 2 clinical trial of TYRA-300 for pediatric achondroplasia (BEACH301), coupled with positive interim clinical proof-of-concept results for TYRA-300 in metastatic urothelial carcinoma from the SURF301 study. The company is advancing multiple Phase 2 studies for TYRA-300, including SURF302 for intermediate-risk non-muscle invasive bladder cancer and BEACH301 for achondroplasia, alongside ongoing SURF201 Phase 1 studies for TYRA-200 and SURF431 for TYRA-430. Tyra Biosciences also completed a $200 million private placement financing in early 2024 to bolster its pipeline development and clinical trial progression. The company maintains a robust clinical pipeline with a focus on targeting resistance mechanisms in oncology and genetically defined conditions, supported by strategic investor backing from firms including RA Capital Management and Boxer Capital. Tyra operates primarily within the biotechnology industry’s precision oncology segment with a focus on large markets including oncology and rare genetic diseases. Its targeted therapy candidates are designed to address FGFR-driven cancers and skeletal dysplasia conditions. The company conducts its clinical and preclinical operations across the United States with a focus on advancing molecularly targeted therapies that improve patient outcomes through precision medicine. Tyra Biosciences remains publicly traded on the NASDAQ under the ticker symbol TYRA and continues to extend its clinical-stage footprint through systematic clinical trial progression and strategic capital raises.

Company News

  • Tyra Biosciences to Host Conference Call on Initial Results of Oral Dabogratinib from the SURF302 Phase 2 Study for IR NMIBC on September 9, 2026

  • Tyra Biosciences, Inc. (NASDAQ:TYRA) Given Average Rating of “Moderate Buy” by Analysts

  • Algert Global LLC Buys 51,110 Shares of Tyra Biosciences, Inc. $TYRA

  • 5AM Venture Management LLC Acquires Shares of 1,029,298 Tyra Biosciences, Inc. $TYRA

  • Tyra Biosciences: SURF302 Is A Worthwhile Binary Bet

  • Tyra Biosciences Reports Second Quarter 2026 Financial Results and Recent Highlights

  • TYRA BIOSCIENCES AND BCAN ESTABLISH MAY 21 AS UPPER TRACT UROTHELIAL CANCER (UTUC) AWARENESS DAY

  • Tyra Biosciences Stock Has Soared 280% in a Year. One Fund Just Disclosed Buying More Shares

  • Tyra Biosciences, Inc. (TYRA) Presents at Bank of America Global Healthcare Conference 2026 Transcript

  • Tyra Biosciences Reports First Quarter 2026 Financial Results and Recent Highlights

  • Tyra Biosciences to Participate in Upcoming Investor Conferences

  • Tyra Biosciences, Inc. (NASDAQ:TYRA) Given Average Recommendation of “Moderate Buy” by Analysts

  • Tyra Biosciences Announces Appointment of Habib Dable to its Board of Directors

  • Tyra Biosciences (NASDAQ:TYRA) Director Sells $528,486.15 in Stock

  • This Biotech Stock Has Surged 250% in a Year as One Investor Discloses $10 Million New Position

  • Tyra Biosciences Reports Fourth Quarter and Full-Year 2025 Financial Results and Recent Highlights

  • Tyra Biosciences Announces Poster Presentations at the 2026 ASCO® Genitourinary (GU) Cancers Symposium

  • Tyra Biosciences to Participate in Upcoming Investor Conferences

  • AquaBounty Technologies (NASDAQ:AQB) versus Tyra Biosciences (NASDAQ:TYRA) Head to Head Analysis

  • Tyra Biosciences Director Sells 247,000 Shares for $5 Million After 38% Rally