Xenon Pharmaceuticals Inc.

Xenon Pharmaceuticals Inc.

XENE
Xenon Pharmaceuticals Inc.US flagNASDAQ Global Market
53.46
USD
+1.16
- -
4.22BMarket Cap
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
3.01
8.96
1.09
0.12
0.02
- -
0.26
0.93
0.42
0.16
- -
- -
0.09
- -
Basic EPS, GAAP
1.32
4.11
-1.1
-1.48
-1.71
-1.63
-1.54
-0.81
-1.77
-2.06
-2.73
-3.01
-4.36
-4.71
Free Cash Flow per Basic Share
-0.38
-0.4
-1.31
-1.28
-1.61
-1.81
-0.23
-1.47
-1.64
-1.72
-2.34
-2.37
-3.53
-3.77
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-12.17
13.72
2.03
1.97
0.03
2.99
1.72
3.45
9.76
9.62
11.53
7.16
4.46
13.19
Tangible Book Value per Share
-8.63
-23.5
-6.13
-7.06
2
4.92
3.25
4.74
12.43
11.92
13.87
9.69
7.34
16.43
Basic Weighted Avg Shares
9
3
14
15
18
19
26
35
44
61
67
78
79
81
Sales/Revenue/Turnover
27
28
16
2
- -
- -
7
32
18
9
- -
- -
8
- -
Operating Margin (%)
35.5
39.15
-60.1
-1,376.43
-10,474.28
- -
-627.02
-97.31
-428.45
-1,368.91
- -
- -
-4,974.27
- -
Depreciation Expense
1
1
1
1
1
1
- -
1
1
1
2
3
3
2
Net Income, GAAP
12
13
-16
-23
-31
-34
-42
-29
-79
-125
-182
-234
-346
-383
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
43.98
45.89
-101.12
-1,275.49
-9,872.67
- -
-609.09
-89.65
-427.85
-1,328.95
- -
- -
-4,612.13
- -
Working Capital
32
71
58
62
41
117
101
167
545
578
618
600
519
1,067
LT Debt
- -
- -
- -
- -
6
15
12
3
8
10
10
8
6
6
Total Equity
24
73
61
64
36
103
92
171
550
721
928
755
582
1,338
Return on Invested Capital (%)
50.58
22.92
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
-90.47
14.27
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
-43.54
-77.29
-197.98
-108.11
-78
-34.19
-28.29
-24.78
-26.95
-35.27
-75.98
-48.8

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
1
2
2
LT Borrowings
- -
- -
- -
LT Finance Leases
7
6
6
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
77
80
97
Market Capitalization
3,165
3,552
4,734

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
480
561
1,107
Cash, Cash Equivalents & STI
462
549
1,095
Accounts Receivable, Net
1
1
1
Inventories
- -
- -
- -
Total Current Liabilities
38
42
40
Payables & Accruals
26
26
31
ST Debt
1
2
2
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
46.29%
47.84%
-22.94%
Free Cash Flow
94.99%
41.29%
51.75%
Net Income, GAAP
43.58%
70.81%
47.62%
Sales/Revenue/Turnover
- -
- -
-20.5%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
8
- -
- -
- -
8
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.62
-0.75
-0.81
-0.84
-3.01
2025
-0.83
-1.07
-1.15
-1.31
-4.36
2026
-1.17
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Andrea DiFabio
Full Time Employees
316
Sector
Healthcare
Industry
Biotechnology
Address
3650 Gilmore Way Burnaby BC Canada V5G 4W8
IPO Date
Nov 5, 2014
Business
Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neuroscience-focused biopharmaceutical company founded in 1996 and headquartered in Burnaby, British Columbia, Canada, with additional offices in Boston, Massachusetts, engages in the discovery, clinical development, and commercialization of novel therapeutics targeting neurological and psychiatric disorders through ion channel modulation. The company advances a differentiated pipeline led by its flagship product candidate azetukalner, a novel, potent, selective Kv7 potassium channel opener in multiple Phase 3 clinical trials for focal onset seizures (X-TOLE2, X-TOLE3), primary generalized tonic-clonic seizures (X-ACKT), major depressive disorder (X-NOVA2, X-NOVA3), and bipolar depression (X-CEED); early-stage wholly-owned programs include XEN1120, a Kv7 potassium channel opener in Phase 1 for pain, and XEN1701, a Nav1.7 sodium channel inhibitor in Phase 1 for pain, alongside undisclosed preclinical Kv7 openers for epilepsy, pain, and psychiatry, Nav1.7 inhibitors for pain, and Nav1.1 sodium channel openers for Dravet syndrome. It also maintains a partnered program with Neurocrine Biosciences for NBI-921355 (formerly XEN901), a selective Nav1.2/1.6 sodium channel inhibitor in Phase 1 for epilepsy. Xenon serves patients with high unmet needs in epilepsy, depression, bipolar disorder, pain, and related neuropsychiatric conditions across North America and global clinical trial sites. Recent developments include completion of patient randomization in the Phase 3 X-TOLE2 trial for focal onset seizures with topline data expected in early 2026, ongoing recruitment in X-NOVA2/3 for major depressive disorder and X-CEED for bipolar depression, presentation of new long-term safety and efficacy data for azetukalner from the X-TOLE open-label extension at the American Epilepsy Society Annual Meeting in December 2025, and maintenance of a strong cash position of $555.3 million as of September 30, 2025, anticipated to fund operations into 2027 amid elevated R&D expenses for late-stage programs.

Company News

APIChat
  • Xenon Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • Xenon Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • What to Know About This Fund’s New $22 Million Xenon Pharmaceuticals Buy Ahead of an FDA Filing

  • Xenon Pharmaceuticals Inc. (XENE) Presents at Bank of America Global Healthcare Conference 2026 Transcript

  • Xenon Pharmaceuticals Q1 Earnings Call Highlights

  • Xenon Pharmaceuticals Inc. (XENE) Q1 2026 Earnings Call Transcript

  • Xenon Reports Q1 2026 Financial Results and Provides Business Update

  • Xenon MRI Advances as a Cardiopulmonary Biomarker Platform at ATS 2026

  • Xenon Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

  • Xenon to Report Q1 2026 Financial Results on May 7, 2026

  • Xenon's Phase 3 Supports A 'Buy' Despite Its Premium

  • Xenon Presents Azetukalner Phase 3 X-TOLE2 Study Results and 48-Month Long-term Data in Focal Onset Seizures at 2026 AAN Annual Meeting

  • Xenon Presents Azetukalner Phase 3 X-TOLE2 Study Results and 48-Month Long-term Data in Focal Onset Seizures at 2026 AAN Annual Meeting

  • Xenon to Present at Upcoming Investor Conferences

  • Xenon to Highlight Phase 3 X-TOLE2 & Long-Term Data for Azetukalner in Focal Onset Seizures at 2026 AAN Annual Meeting

  • Xenon Pharmaceuticals Target of Unusually High Options Trading (NASDAQ:XENE)

  • Xenon Pharma Stock Up 55% as Insider Sells $78K in Shares. Here's What Investors Should Know

  • Xenon Pharmaceuticals Stock Soars 20% in 3 Months: Here's Why

  • Xenon Pharmaceuticals Inc. $XENE Shares Sold by Bamco Inc. NY

  • This Fund Has a $200 Million Bet on a Biotech Stock Up 30% in Days After Phase 3 Breakthrough