CRISPR Therapeutics AG

CRISPR Therapeutics AG

CRSP
CRISPR Therapeutics AGUS flagNASDAQ Global Market
55.79
USD
-0.70
- -
5.38BMarket Cap
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
0.01
0.42
1.02
0.07
5.32
0.01
12.02
0.01
4.67
0.41
- -
0.12
Basic EPS, GAAP
-0.23
-0.88
-1.89
-1.71
-3.44
1.23
-5.29
4.97
-8.36
-1.94
-4.34
-6.47
-4.76
Free Cash Flow per Basic Share
-0.16
1.99
-4.56
-1.94
-2.06
0.92
-3.89
6.02
-6.85
-3.44
-1.71
-4.12
-3.92
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-0.18
-0.73
5.86
4.63
7.56
15.46
22.52
31.17
23.89
23.52
22.53
20.04
18.07
Tangible Book Value per Share
-0.19
-0.74
5.85
4.62
7.56
15.45
22.51
31.16
23.89
23.52
22.53
20.04
18.07
Basic Weighted Avg Shares
29
29
12
40
48
54
66
76
78
79
84
90
95
Sales/Revenue/Turnover
- -
- -
5
41
3
290
1
913
- -
370
35
- -
11
Operating Margin (%)
- -
-10,416.6
-1,319.33
-157.69
-5,087.8
16.14
-65,273.48
40.91
-154,394.72
-60.15
-1,333.05
- -
-4,857.64
Depreciation Expense
- -
- -
1
3
4
5
9
18
24
20
19
19
19
Net Income, GAAP
-7
-26
-23
-68
-165
67
-349
378
-650
-154
-366
-582
-451
Effective Tax Rate (%)
- -
- -
- -
- -
- -
0.67
- -
0.49
- -
- -
- -
- -
- -
Profit Margin (%)
- -
-10,456.68
-449.3
-166.74
-5,281.08
23.09
-64,247.7
41.36
-149,122.71
-41.52
-1,046.43
- -
-4,101.26
Working Capital
-1
147
298
234
439
930
1,622
2,298
1,732
1,799
1,849
1,837
2,239
LT Debt
- -
38
- -
- -
- -
44
50
213
228
223
206
188
765
Total Equity
-7
-29
233
188
392
939
1,664
2,399
1,875
1,883
1,932
1,922
1,747
Return on Invested Capital (%)
- -
- -
- -
- -
- -
6.7
- -
17.04
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
9.66
- -
17.36
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
-32.5
-56.89
10.04
-26.8
18.59
-30.42
-8.17
-19.2
-30.18
-26.09

Capital Structure

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
ST Debt
19
19
19
LT Borrowings
- -
585
586
LT Finance Leases
188
184
179
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
96
96
97
Market Capitalization
5,029
4,585
5,272

Working Capital

FRC

in mil. unless spec.
Dec'25
Mar'26
Jun'26
Total Current Assets
1,986
2,448
2,372
Cash, Cash Equivalents & STI
1,976
2,442
2,364
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
149
136
133
Payables & Accruals
102
89
82
ST Debt
19
19
19
Deferred Revenue
16
15
15

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
-56.85%
4.96%
-0.53%
Free Cash Flow
-132.74%
-86.81%
156.39%
Net Income, GAAP
-79.61%
-71.91%
58.8%
Sales/Revenue/Turnover
- -
- -
- -
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
35
35
2025
- -
- -
- -
- -
- -
2026
1
10
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-1.43
-1.49
-1.01
-0.44
-4.34
2025
-1.58
-2.4
-1.17
-1.37
-6.47
2026
-1.28
-0.94
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

CEO
Samarth Kulkarni
Full Time Employees
393
Sector
Healthcare
Industry
Biotechnology
Address
Baarerstrasse 14 Zug ZG Switzerland 6300
IPO Date
Oct 19, 2016
Business
CRISPR Therapeutics AG (Nasdaq: CRSP) is a biotechnology company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 gene-editing platform. Founded in 2013 and headquartered in Zug, Switzerland, the company operates globally with research and development facilities in Boston and San Francisco, California, and a state-of-the-art manufacturing site in Framingham, Massachusetts. Its lead approved therapy, exagamglogene autotemcel (exa-cel, commercialized as CASGEVY in collaboration with Vertex Pharmaceuticals), is an autologous ex vivo CRISPR/Cas9 gene-edited cell therapy approved in multiple countries for eligible patients with sickle cell disease and transfusion-dependent beta-thalassemia; the company advances a broad pipeline including wholly owned and partnered programs across hemoglobinopathies such as next-generation conditioning agents and in vivo HSC editing; immuno-oncology and autoimmune therapies like CTX112 (anti-CD19 allogeneic CAR T) and other CAR T candidates targeting CD19, CD70, and glypican-3; in vivo cardiovascular programs including CTX310 (ANGPTL3), CTX320 (Lp(a)), and CTX340 (AGT for refractory hypertension); additional in vivo candidates such as CTX450 (ALAS1 for acute hepatic porphyria), CTX460 (SERPINA1 for alpha-1 antitrypsin deficiency), and undisclosed programs in rare and common diseases; regenerative medicine offerings like CTX211 and CTX213 (allogeneic gene-edited stem cell-derived therapies for type 1 diabetes); and partnered siRNA and other initiatives including SRSD107 (Factor XI for thromboembolic conditions with Sirius Therapeutics) and programs in Duchenne muscular dystrophy, myotonic dystrophy type 1, cystic fibrosis, and type 1 diabetes licensed to Vertex. In 2025, CRISPR Therapeutics expanded its portfolio through a strategic collaboration with Sirius Therapeutics, involving a $25 million cash upfront and $70 million equity investment to co-develop and commercialize novel siRNA therapies starting with SRSD107, with options for two additional programs and shared costs/profits; the company also continues global commercialization of CASGEVY, achieving regulatory approvals in nine countries and treating over 100 patients as of mid-2025 while advancing clinical milestones for CTX112, CTX310, CTX320, and others amid strong cash reserves exceeding $1.7 billion.

Company News

  • 2 Reasons CRISPR Therapeutics Stock Could Soar in the Final 4 Months of 2026

  • Why Is CRISPR Therapeutics (CRSP) Up 7.1% Since Last Earnings Report?

  • Next Biotech Boom May Be Cancer Vaccines: Watch These ETFs

  • CRISPR Therapeutics Presents Phase 1a Data for CTX310® Demonstrating Deep and Durable ANGPTL3 Editing, Triglyceride and LDL Lowering at ESC Congress 2026

  • 4 Gene-Editing Biotech Stocks Worth Watching for Long-Term Gains

  • Bank of America Corp DE Decreases Stock Position in CRISPR Therapeutics AG $CRSP

  • Agomab Announces Proposed Appointments of Marino Garcia and Dr. Naimish Patel to Board of Directors

  • CRISPR: "Strong Buy" CASGEVY Sales Growth And In Vivo Expansion With CTX310

  • CRISPR Therapeutics' Q2 Earnings & Revenues Surpass Estimates

  • CRISPR Therapeutics AG (CRSP) Reports Q2 Loss, Tops Revenue Estimates

  • CRISPR Therapeutics Provides Business Update and Reports Second Quarter 2026 Financial Results

  • CRISPR Therapeutics AG (CRSP) Exceeds Market Returns: Some Facts to Consider

  • Morgan Stanley Nearly Doubled Its Price Target for CRISPR Therapeutics. Is the Gene-Editing Stock a No-Brainer Buy?

  • 3 Stocks With the Most Upside by the End of 2026

  • CRISPR Therapeutics AG (CRSP) is Attracting Investor Attention: Here is What You Should Know

  • CRISPR Therapeutics AG (CRSP) Expected to Beat Earnings Estimates: Can the Stock Move Higher?

  • CRISPR Therapeutics AG (CRSP) Stock Sinks As Market Gains: What You Should Know

  • Cathie Wood's $362 Million CRISPR Therapeutics Bet Isn't Just Bold -- It's Backed by a Catalyst Many Investors Are Underrating

  • CRISPR Therapeutics AG $CRSP Shares Sold by Amova Asset Management Americas Inc.

  • Crispr Therapeutics: A Catalyst-Rich 12 Months Ahead