Cyclerion Therapeutics, Inc.

Cyclerion Therapeutics, Inc.

CYCN
Cyclerion Therapeutics, Inc.US flagNASDAQ Global Select
3.70
USD
+0.05
- -
16.00MMarket Cap
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
- -
- -
3.29
1.51
1.7
0.14
- -
0.79
0.65
0.57
Basic EPS, GAAP
-68.8
-84.42
-89.85
-51.18
-26.39
-20.28
-2.25
-1.21
-1.11
-1.51
Free Cash Flow per Basic Share
-60.52
-73.94
-79.7
-48.69
-18.66
-18.69
-9.09
-1.72
-1.04
-1.03
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
- -
- -
-62.55
-107.51
-109.89
-119.26
-113.1
-106.23
-85.2
-78.33
Tangible Book Value per Share
-6.28
-7.65
71.39
39.14
24.65
4.81
4.83
3.51
2.86
1.94
Basic Weighted Avg Shares
1
1
1
2
2
2
2
3
3
4
Sales/Revenue/Turnover
- -
- -
5
2
3
- -
- -
2
2
2
Operating Margin (%)
- -
- -
-2,774.28
-3,612.11
-1,635.96
-6,242.42
- -
-181.4
-239.78
-337.43
Depreciation Expense
2
2
3
2
- -
- -
- -
- -
- -
- -
Net Income, GAAP
-94
-115
-123
-78
-52
-44
-5
-3
-4
-5
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Profit Margin (%)
- -
- -
-2,729.27
-3,388.59
-1,555.63
-14,841.08
- -
-152.85
-170.11
-264.73
Working Capital
-13
-17
83
42
44
7
6
4
4
1
LT Debt
- -
- -
70
39
- -
- -
- -
- -
- -
- -
Total Equity
-9
-10
98
59
48
10
11
9
9
7
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
- -
- -
- -
LT Borrowings
- -
- -
- -
LT Finance Leases
- -
- -
- -
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
4
4
4
Market Capitalization
7
4
5

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
5
5
3
Cash, Cash Equivalents & STI
5
3
3
Accounts Receivable, Net
- -
1
- -
Inventories
- -
- -
- -
Total Current Liabilities
1
1
2
Payables & Accruals
1
1
2
ST Debt
- -
- -
- -
Deferred Revenue
- -
- -
- -

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
- -
-21.64%
2.66%
Free Cash Flow
- -
-38.05%
-23.52%
Net Income, GAAP
- -
-32.57%
15.41%
Sales/Revenue/Turnover
- -
- -
3.7%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
2
2
2025
- -
- -
1
1
2
2026
- -
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-0.62
-0.53
-0.29
- -
-1.21
2025
-0.56
-0.11
-0.3
- -
-1.11
2026
-0.76
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChatGPT
CEO
Regina Graul
Full Time Employees
1
Sector
Healthcare
Industry
Biotechnology
Address
245 First Street Cambridge MA United States of America 02142
IPO Date
Mar 18, 2019
Business
Cyclerion Therapeutics, Inc. is a clinical-stage biopharmaceutical entity that has recently undergone a strategic transformation to concentrate on developing innovative therapies for neuropsychiatric conditions. The company’s core focus has shifted to building a new pipeline, with its foundational product candidate being an individualized therapeutic approach for treatment-resistant depression (TRD). This lead program, which is Phase 2-ready, leverages common anesthetic agents alongside a proprietary, technology-driven system to restore functional connectivity by resynchronizing communication between key brain regions. A Phase 2 proof-of-concept trial for this program is projected to commence in 2026, with initial data anticipated in 2027. This strategic pivot follows a licensing agreement with the Massachusetts Institute of Technology (MIT) and a move away from its historical portfolio of soluble guanylate cyclase (sGC) stimulators, such as CY6463, Praliciguat, and Olinciguat, which have been out-licensed or sold to other entities. Founded in 2019, the company maintains its headquarters in Cambridge, Massachusetts.

Company News

APIChatGPT
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