Prothena Corporation plc

Prothena Corporation plc

PRTA
Prothena Corporation plcUS flagNASDAQ Global Select
9.19
USD
-0.40
- -
481.13MMarket Cap
2013 Y
2014 Y
2015 Y
2016 Y
2017 Y
2018 Y
2019 Y
2020 Y
2021 Y
2022 Y
2023 Y
2024 Y
2025 Y
TTM
Revenue per Share
0.04
2.06
0.05
0.03
0.73
0.02
0.02
0.02
4.54
1.14
1.72
2.51
0.18
1.08
Basic EPS, GAAP
-2.2
-0.29
-2.66
-4.66
-4.07
-3.93
-1.95
-2.78
1.51
-2.47
-2.76
-2.27
-4.53
-2.81
Free Cash Flow per Basic Share
-1.75
-0.05
-1.98
-3.87
-3.58
-0.76
-1.34
-2.02
2.08
-2.31
-2.57
-2.8
-3.04
-1.51
Dividend per Share
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
Book Value per Share
-2.21
-1.95
-4.25
-8.41
-11.74
-15.11
-16.84
-19.61
-16.18
-17.57
-18.41
-20.49
-25
-24.41
Tangible Book Value per Share
9.31
11.75
11.89
10.64
10.81
8.16
6.84
4.61
10.54
13.13
10.55
9.06
5.21
5.81
Basic Weighted Avg Shares
19
25
30
34
38
40
40
40
44
47
53
54
54
54
Sales/Revenue/Turnover
1
51
2
1
28
1
1
1
201
54
91
135
10
58
Operating Margin (%)
-5,980.33
-13.07
-4,974.3
-15,121.8
-564.17
-14,943.46
-10,535.38
-13,216.18
35.88
-244.05
-209.08
-114.36
-1,905.82
-160.84
Depreciation Expense
1
1
1
2
3
3
7
2
1
1
1
1
1
1
Net Income, GAAP
-41
-7
-81
-160
-153
-156
-78
-111
67
-117
-147
-122
-244
-151
Effective Tax Rate (%)
- -
- -
- -
- -
- -
- -
- -
- -
6.88
- -
- -
- -
- -
- -
Profit Margin (%)
-6,064.5
-14.06
-5,016.3
-15,176.11
-556.84
-16,297.91
-9,542.63
-13,029.78
33.39
-216.95
-160.91
-90.49
-2,520.57
-260.92
Working Capital
171
287
355
350
389
416
361
273
551
669
582
437
274
307
LT Debt
- -
- -
- -
51
52
50
18
12
6
- -
11
8
5
5
Total Equity
173
290
361
365
407
323
273
184
466
622
561
487
280
313
Return on Invested Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
19.71
- -
- -
- -
- -
- -
Return on Capital (%)
- -
- -
- -
- -
- -
- -
- -
- -
-9.12
- -
- -
- -
- -
12.3
Return on Common Equity (%)
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -
- -

Capital Structure

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
ST Debt
3
3
3
LT Borrowings
- -
- -
- -
LT Finance Leases
6
5
5
Preferred Equity and Hybrid Capital
- -
- -
- -
Shares Outstanding
54
54
53
Market Capitalization
525
514
523

Working Capital

FRC

in mil. unless spec.
Sep'25
Dec'25
Mar'26
Total Current Assets
340
315
339
Cash, Cash Equivalents & STI
331
308
329
Accounts Receivable, Net
- -
- -
- -
Inventories
- -
- -
- -
Total Current Liabilities
51
41
33
Payables & Accruals
28
22
18
ST Debt
3
3
3
Deferred Revenue
3
3
2

Growth Rates

FRC

in mil. unless spec.

(avg. rate of change)

10 years
5 years
1 year
Total Equity
6.53%
24.27%
-42.4%
Free Cash Flow
-21.51%
-77.81%
8.89%
Net Income, GAAP
-23.75%
-65.28%
99.57%
Sales/Revenue/Turnover
2,573.33%
4,673.15%
-92.83%
Total Cash Common Dividend
- -
- -
- -

Quarterly Revenue

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
132
1
2
135
2025
3
4
2
- -
10
2026
51
- -
- -
- -
- -

Quarterly Earnings Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
-1.34
1.24
-1.1
-1.08
-2.27
2025
-1.12
-2.34
-0.68
-0.4
-4.53
2026
0.61
- -
- -
- -
- -

Quarterly Dividends Per Share

FRC

in mil. unless spec.

Year

Q1
Q2
Q3
Q4
FY
2024
- -
- -
- -
- -
- -
2025
- -
- -
- -
- -
- -
2026
- -
- -
- -
- -
- -

Company Description

APIChat
CEO
Gene G. Kinney
Full Time Employees
163
Sector
Healthcare
Industry
Biotechnology
Address
77 Sir John Rogerson’s Quay Dublin United States of America 2
IPO Date
Dec 18, 2012
Business
Prothena Corporation plc, a clinical-stage biotechnology company focused on the discovery and development of novel investigational therapies targeting protein dysregulation in neurodegenerative and rare peripheral amyloid diseases, advances a pipeline including PRX012, an anti-amyloid beta monoclonal antibody in Phase 1 for early Alzheimer's disease with data expected in 2025; prasinezumab, a humanized monoclonal antibody targeting alpha-synuclein in Phase 2b for Parkinson's disease and other synucleinopathies; coramitug for transthyretin amyloidosis (ATTR-CM); BMS-986446 and PRX019 targeting tau and TDP-43 respectively in collaboration with Bristol Myers Squibb; and PRX123, a preclinical dual amyloid beta-tau vaccine. The company, founded in 2012 through a spin-off from Elan Corporation plc and headquartered in Dublin, Ireland, with research operations in South San Francisco, California, serves patient populations affected by devastating conditions such as Alzheimer's disease, Parkinson's disease, ALS, and ATTR amyloidosis primarily in the United States and globally through partnerships. Recent developments include the discontinuation of the birtamimab program for AL amyloidosis following the Phase 3 AFFIRM-AL trial failure, a shift emphasizing PRX012 as the lead wholly-owned asset with higher-dose subcutaneous formulations advancing toward topline results in August 2025; progression of partnered programs with Roche on prasinezumab potentially entering Phase 3 by year-end 2025, Novo Nordisk's Phase 2 data for coramitug in the second half of 2025, and Bristol Myers Squibb's ongoing tau and TDP-43 efforts; and initiation of a Phase 1 trial for PRX019 in Q3 2025 alongside a poster presentation on its TDP-43 program at Neuroscience 2025.

Company News

APIChat
  • Prothena Posts Q1 Earnings as Revenues Surge on Milestone Payment

  • Prothena Reports First Quarter 2026 Financial Results and Business Highlights

  • Prothena Announces Novo Nordisk Obtains Fast Track Designation from the U.S. FDA for Coramitug (PRX004) in ATTR Amyloidosis with Cardiomyopathy

  • Prothena Announces Leadership Team Updates

  • Wall Street Analysts Think Prothena (PRTA) Could Surge 120.19%: Read This Before Placing a Bet

  • Prothena Partners Present Data Supporting Next Generation Treatments for Parkinson's and Alzheimer's Disease at AD/PD™ 2026

  • Prothena Announces Achievement of $50 Million Clinical Milestone Payment from Novo Nordisk Related to Ongoing Phase 3 Clinical Trial for Coramitug (Formerly PRX004) in ATTR Amyloidosis with Cardiomyopathy

  • Prothena: A Hold With 2 Late-Stage Programs Underway But With Caution

  • Wall Street Analysts Believe Prothena (PRTA) Could Rally 118.09%: Here's is How to Trade

  • Prothena Announces up to $100 Million Share Repurchase Plan

  • Prothena Q4 Earnings Meet Estimates, Pipeline Progress in Focus

  • Prothena Corporation plc (PRTA) Q4 2025 Earnings Call Transcript

  • Prothena (PRTA) Reports Q4 Loss, Lags Revenue Estimates

  • Prothena Reports Fourth Quarter and Full Year 2025 Financial Results, and Provides Financial Guidance and Business Highlights

  • Prothena Stock Tumbles 36.8% Year Over Year: What Lies Ahead?

  • FTRE vs. PRTA: Which Stock Is the Better Value Option?

  • Prothena to Report Fourth Quarter and Full Year 2025 Financial Results on February 19, 2026

  • All You Need to Know About Prothena (PRTA) Rating Upgrade to Buy

  • 89,704 Shares in Prothena Corporation plc $PRTA Acquired by Assenagon Asset Management S.A.

  • Squarepoint Ops LLC Takes $1.27 Million Position in Prothena Corporation plc $PRTA