Vertex Pharmaceuticals Incorporated Financial Ratios — VRTX

Profitability (USD)

	2011 Y	2012 Y	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2011	12/31/2012	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Return on Common Equity (%)	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	115.24	68.29	43.43	-5.42	34.12
Return on Assets (%)	1.51	-4.31	-17.53	-31.74	-23.02	-4.15	8.18	42.83	16.16	27.02	18.6	21.04	17.71	-2.37	16.41
Return on Capital (%)	-1.53	- -	- -	- -	- -	- -	- -	- -	-68.33	913.96	80.31	58.04	39.79	-5.39	29.42
Return on Invested Capital (%)	12.39	- -	- -	- -	- -	- -	- -	- -	17.07	30.18	22.7	25.45	18.69	2.73	19.83
Gross Margin (%)	94.29	81.67	89.25	89.49	87.94	87.64	88.95	86.56	86.84	88.14	88.06	87.9	87.21	86.11	86.24
EBITDA Margin (%)	18.2	5.68	-8.93	-99.62	-38.97	4.26	18.25	24.16	31.44	48	38.35	49.25	40.14	-0.24	39.7
Operating Margin (%)	15.72	3.18	-12.92	-110.52	-45.01	0.66	15.78	21.79	28.87	46.24	36.69	47.59	38.31	-2.12	37.95
Incremental Operating Margin (%)	72.3	-148.71	- -	- -	- -	71.04	48.52	48.51	48.25	81.62	-6.6	108.45	-50.03	7.6	487.95
Pretax Margin (%)	4.28	2.1	-51.65	-126.61	-54.03	-3.96	-0.63	19.7	33.51	50.23	36.05	47.39	44.38	2.25	38.69
Profit Margin (%)	2.1	-7.01	-36.72	-127.25	-53.89	-6.58	10.59	68.8	28.27	43.7	30.92	37.2	36.68	-4.86	32.94
Net Income to Common Margin (%)	2.1	-7.01	-36.72	-127.25	-53.89	-6.58	10.59	68.8	28.27	43.7	30.92	37.2	36.68	-4.86	32.94
Effective Tax Rate (%)	31.87	- -	- -	- -	- -	- -	- -	- -	15.64	13	14.22	21.51	17.36	315.53	14.86
Dvd Payout Ratio (%)	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Sustainable Growth Rate (%)	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	115.24	68.29	43.43	-5.42	34.12

Credit (USD)

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	2011 Y	2012 Y	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2011	12/31/2012	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Total Debt	456	697	507	825	826	841	606	587	662	932	967	900	808	1,744	2,030
ST Debt	- -	14	17	32	87	319	23	5	39	42	80	89	84	87	77
LT Debt	456	683	490	793	739	521	584	582	623	890	887	810	725	1,657	1,953
Total Debt/EBITDA	1.78	8.03	-4.68	-1.43	-2.05	11.58	1.34	0.8	0.51	0.31	0.33	0.2	0.2	-66.58	0.43
Net Debt/EBITDA	-0.29	-1.03	5.26	0.57	1.04	-12.18	-3.67	-3.6	-2.38	-2.01	-2.34	-2.39	-2.62	174.41	-1.07
Total Debt/EBIT	2.06	14.35	-3.24	-1.29	-1.78	75.08	1.54	0.88	0.55	0.32	0.35	0.21	0.21	-7.47	0.45
Net Debt/EBIT	-0.34	-1.84	3.64	0.52	0.9	-78.94	-4.24	-3.99	-2.59	-2.09	-2.45	-2.47	-2.74	19.58	-1.12
EBITDA to Interest Expense	6.81	5.77	-4.72	-7.94	-4.78	0.89	6.55	10.16	22.37	51.18	47.23	80.26	89.83	-0.86	358.21
EBITDA-CapEx/Interest Expense	4.3	1.04	-6.96	-8.64	-5.32	0.2	2.81	8.84	21.09	46.72	43.41	76.52	83.98	-16.72	325.31
EBIT to Interest Expense	5.88	3.23	-6.83	-8.8	-5.52	0.14	5.67	9.16	20.55	49.3	45.19	77.55	85.72	-7.63	342.44
Interest Expense	38	15	23	73	84	81	69	72	58	58	62	55	44	31	13
Common Equity/Total Assets	-154.82	-127.56	-170.96	-201.44	-210.49	-185.43	-144.31	-47.82	-22.24	7.33	23.85	35.95	44.63	42.65	52.89
Long-Term Debt/Equity (%)	49.11	57.13	36.1	72.34	67.61	38.96	28.59	13.11	10.24	10.24	8.78	5.82	4.12	10.1	10.46
Long-Term Debt/Capital (%)	-16.2	-26.02	-14.16	-20.56	-17.28	-11.99	-12.98	-24.23	-52.4	49.6	21.27	10.91	6.62	14.6	12.53
Long-Term Debt/Total Assets (%)	20.68	24.76	21.12	33.96	29.59	18	16.47	9.31	7.49	7.57	6.6	4.46	3.19	7.35	7.62
Total Debt/Equity (%)	49.11	58.28	37.35	75.26	75.55	62.83	29.69	13.23	10.87	10.73	9.58	6.47	4.6	10.63	10.88
Total Debt/Capital (%)	-16.2	-26.54	-14.65	-21.39	-19.31	-19.33	-13.49	-24.45	-55.66	51.97	23.2	12.12	7.38	15.36	13.02
Total Debt/Total Assets (%)	20.68	25.26	21.84	35.33	33.07	29.02	17.1	9.4	7.95	7.93	7.2	4.96	3.56	7.74	7.92
Net Debt to Equity	-8.11	-7.48	-41.97	-30.15	-38.37	-66.06	-81.55	-59.75	-51.1	-68.93	-67.28	-75.5	-58.98	-27.85	-27.24
Net Debt/Capital (%)	2.29	2.87	14.14	7.37	8.4	15.98	27.03	52.48	72.34	142.75	258.93	341.16	-1,774.62	-67.36	-48.39
EBITDA	257	87	-108	-578	-402	73	454	736	1,309	2,979	2,905	4,398	3,962	-26	4,764
EBITDA-CapEx	162	16	-160	-629	-448	16	195	641	1,234	2,719	2,670	4,194	3,703	-512	4,327
Operating Income (Loss)	222	49	-157	-641	-465	11	393	664	1,202	2,869	2,779	4,250	3,780	-233	4,554

Liquidity (USD)

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	2011 Y	2012 Y	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2011	12/31/2012	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Cash Ratio	2.47	3.05	3.68	3.77	2.06	1.81	2.59	2.83	2.85	3.55	3.51	3.93	3.16	1.72	1.71
Current Ratio	3.39	3.67	3.99	4.2	2.78	2.31	3.28	3.43	3.61	4.33	4.46	4.83	3.99	2.69	2.9
Quick Ratio	2.94	3.39	3.92	4.01	2.43	2.11	3.07	3.19	3.33	4.02	4.04	4.46	3.6	2.17	2.24
CFO/Avg Current Liab	0.33	0.65	-0.15	-1.5	-0.84	0.36	1.06	1.32	1.28	2.03	1.32	1.69	1.12	-0.14	0.98
Common Equity/Total Assets	-154.82	-127.56	-170.96	-201.44	-210.49	-185.43	-144.31	-47.82	-22.24	7.33	23.85	35.95	44.63	42.65	52.89
Long-Term Debt/Equity (%)	49.11	57.13	36.1	72.34	67.61	38.96	28.59	13.11	10.24	10.24	8.78	5.82	4.12	10.1	10.46
Long-Term Debt/Capital (%)	-16.2	-26.02	-14.16	-20.56	-17.28	-11.99	-12.98	-24.23	-52.4	49.6	21.27	10.91	6.62	14.6	12.53
Long-Term Debt/Total Assets (%)	20.68	24.76	21.12	33.96	29.59	18	16.47	9.31	7.49	7.57	6.6	4.46	3.19	7.35	7.62
Total Debt/Equity (%)	49.11	58.28	37.35	75.26	75.55	62.83	29.69	13.23	10.87	10.73	9.58	6.47	4.6	10.63	10.88
Total Debt/Capital (%)	-16.2	-26.54	-14.65	-21.39	-19.31	-19.33	-13.49	-24.45	-55.66	51.97	23.2	12.12	7.38	15.36	13.02
Total Debt/Total Assets (%)	20.68	25.26	21.84	35.33	33.07	29.02	17.1	9.4	7.95	7.93	7.2	4.96	3.56	7.74	7.92
CFO/Total Liabilities	11.27	17.13	-6.3	-46.27	-26.01	15.15	56.19	70.15	70.27	106.15	79.32	97.44	68.69	-8.04	52.05
CFO/CapEx	1.52	3.76	-1.18	-11.19	-8.07	4.17	3.26	13.31	20.81	12.52	11.25	20.18	13.69	-1.01	8.3
Altman's Z-Score	2.2	2.51	8.92	10.58	9.83	5.17	14.54	14.66	16.51	14.38	12.69	13.18	14.58	11.68	12.24

Working Capital (USD)

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	2011 Y	2012 Y	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2011	12/31/2012	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Accounts Receivable Turnover	14.42	9.36	10.6	7.19	8.27	9.1	10.33	8.82	7.98	8.17	7.49	6.93	6.57	6.95	6.55
Days Sales Outstanding	25.31	39.01	34.45	50.77	44.16	40.12	35.32	41.38	45.73	44.67	48.72	52.7	55.58	52.54	55.69
Inventory Turnover	1.43	3.92	5.84	2.71	2.83	3.12	2.9	3.47	3.75	3.28	2.85	2.66	2.1	1.57	1.14
Days Inventory Outstanding	254.87	93.17	62.49	134.64	129.06	116.9	125.66	105.25	97.23	111.12	127.94	137.46	173.42	231.83	319.64
Accounts Payable Turnover	3.49	2.25	1.51	1.29	2.06	3.39	4.57	4.56	5.95	7	5.58	4.76	4.61	5.13	4.88
Accounts Payable Turnover Days	104.52	162.23	241.21	283.12	176.77	107.82	79.91	79.98	61.33	52.14	65.43	76.65	79.24	71.09	74.85
Cash Conversion Cycle	175.67	-30.05	-144.27	-97.7	-3.55	49.2	81.08	66.65	81.64	103.65	111.24	113.51	149.76	213.29	300.48
Inventory to Cash Days	-229.56	-54.17	-28.05	-83.87	-84.9	-76.78	-90.34	-63.87	-51.5	-66.45	-79.22	-84.76	-117.84	-179.29	-263.95
Inventories	112	30	14	31	57	78	112	124	168	281	353	461	739	1,205	1,687
Raw Materials	32	4	- -	9	9	6	21	10	26	46	42	38	79	252	260
Work In Process	47	11	10	21	41	57	74	88	107	161	224	261	525	769	1,197
Finished Goods	33	15	4	2	8	15	17	27	34	73	87	162	135	185	230
Other Inventory	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -

Enterprise Value (USD)

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	2011 Y	2012 Y	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2011	12/31/2012	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Market Capitalization	6,804	8,881	16,711	27,954	30,364	18,026	37,294	42,139	56,211	61,411	56,591	73,957	104,856	103,856	115,924
- Cash & Cash Equivalents	475	489	569	625	715	1,184	1,665	2,650	3,109	5,988	6,795	10,504	10,369	4,570	5,085
+ Preferred Equity and Hybrid Capital	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
+ Minority/Non Controlling Interest	142	197	- -	21	154	182	14	- -	- -	- -	- -	- -	- -	- -	- -
+ Total Debt	456	697	507	825	826	841	606	587	662	932	967	900	808	1,744	2,030
Enterprise Value	6,433	8,453	15,752	27,413	30,302	17,614	35,825	39,557	53,064	55,684	50,033	64,078	94,446	99,485	111,347
Total Capital	-2,815	-2,626	-3,458	-3,857	-4,279	-4,349	-4,497	-2,400	-1,189	1,793	4,171	7,425	10,953	11,354	15,593
Total Debt/Capital (%)	-16.2	-26.54	-14.65	-21.39	-19.31	-19.33	-13.49	-24.45	-55.66	51.97	23.2	12.12	7.38	15.36	13.02
Total Debt / EV	0.07	0.08	0.03	0.03	0.03	0.05	0.02	0.01	0.01	0.02	0.02	0.01	0.01	0.02	0.02
EV/Sales	4.56	5.54	13	47.23	29.35	10.35	14.4	12.98	12.75	8.97	6.61	7.17	9.57	9.03	9.28
EV/EBITDA	25.06	97.43	- -	- -	- -	242.63	78.87	53.72	40.54	18.69	17.23	14.57	23.84	21.62	23.37
EV/EBIT	29.02	174.03	- -	- -	- -	1,572.94	91.2	59.58	44.15	19.41	18	15.08	24.98	22.64	24.45
EV/Cash Flow to Firm	37.97	29.87	- -	- -	- -	52.16	81.39	25.99	32.78	16.85	18.56	15.36	26.43	- -	30.57
EV/Free Cash Flow to Firm	24.37	23.87	1,717.81	- -	- -	44.68	51.21	24.45	31.32	15.62	17.07	14.64	24.65	- -	27.29
Diluted Market Cap	6,934	8,881	16,711	27,954	30,364	18,026	37,948	42,950	57,074	62,251	57,074	74,823	105,995	103,856	116,967
Diluted Enterprise Value	7,057	9,285	16,648	28,175	30,629	17,864	36,903	40,886	54,627	57,195	51,246	65,219	96,434	101,031	113,913
EV per Share	31.4	39.88	70.04	116.5	125.57	71.99	143.96	155.56	206.69	214.3	194.15	250.21	366.49	385.75	435.46
TTM Sales	1,411	1,527	1,212	580	1,032	1,702	2,489	3,048	4,163	6,206	7,574	8,931	9,869	11,020	12,001
TTM EBITDA	257	87	-108	-578	-402	73	454	736	1,309	2,979	2,905	4,398	3,962	-26	4,764
TTM Operating Income	222	49	-157	-641	-465	11	393	664	1,202	2,869	2,779	4,250	3,780	-233	4,554
TTM Cash Flow to Firm	169	283	-42	-500	-277	338	440	1,522	1,619	3,304	2,696	4,173	3,574	-559	3,643
TTM Free Cash Flow to Firm	264	354	9	-448	-231	394	700	1,618	1,694	3,564	2,931	4,378	3,832	-73	4,080

Multiples (USD)

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	2011 Y	2012 Y	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2011	12/31/2012	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Price/Free Cash Flow	29.1	26.2	-1,802.06	-53.56	-94.85	61.59	34.36	31.45	34.7	17.72	19.83	17.26	27.92	-14,424.49	28.75
EV/EBIT	29.02	174.03	- -	- -	- -	1,572.94	91.2	59.58	44.15	19.41	18	15.08	24.98	22.64	24.45
Enterprise Value	6,433	8,453	15,752	27,413	30,302	17,614	35,825	39,557	53,064	55,684	50,033	64,078	94,446	99,485	111,347
Low Price	26.5	32.04	42.72	59.79	97.45	71.46	73.34	144.07	160.95	197.47	176.36	214.66	282.21	377.85	362.5
EV/Sales	4.56	5.54	13	47.23	29.35	10.35	14.4	12.98	12.75	8.97	6.61	7.17	9.57	9.03	9.28
EV/EBITDA	25.06	97.43	- -	- -	- -	242.63	78.87	53.72	40.54	18.69	17.23	14.57	23.84	21.62	23.37
Price/Earnings	230.08	- -	- -	- -	- -	- -	141.54	20.1	47.77	22.65	24.16	22.26	28.97	- -	29.32
Price/Earnings Average	305.01	-93.83	-34.38	-28.51	-53.69	-192.56	119.86	20.3	40.3	24.1	22.49	21.17	24.15	-216.95	28.68
Price/Earnings High	407.86	-130.89	-45.46	-39.62	-62.22	-272.87	158.54	23.64	49.23	29.33	26.74	25.04	29.4	-250.33	33.61
Price/Earnings Low	183.59	-63.45	-21.59	-19.05	-42.27	-156.05	69.27	17.47	35.11	18.92	19.4	16.55	20.09	-181.94	23.45
Price/Book Value	-1.99	-2.52	-4.21	-5.94	-5.77	-3.36	-7.29	-14.11	-30.38	71.3	17.67	11.33	10.34	10.81	8.55
Price/Book Value Average	-2.64	-2.85	-3.86	-4.48	-5.68	-4.02	-6.17	-14.25	-25.63	75.89	16.45	10.78	8.62	12.09	8.36
Price/Book Value High	-3.53	-3.98	-5.1	-6.22	-6.58	-5.69	-8.16	-16.59	-31.31	92.34	19.55	12.75	10.49	13.95	9.8
Price/Book Value Low	-1.59	-1.93	-2.42	-2.99	-4.47	-3.26	-3.57	-12.27	-22.33	59.57	14.19	8.42	7.17	10.14	6.83
Price/Tangible Book Value	29.08	17.71	12.61	27.21	40.01	17.96	19	9.61	12	8.43	6.51	6.05	6.7	7.16	6.76
Price/Tangible Book Value Average	38.55	20.03	11.54	20.5	39.36	21.5	16.09	9.71	10.13	8.97	6.06	5.75	5.58	8.02	6.61
Price/Tangible Book Value High	51.55	27.94	15.27	28.48	45.61	30.47	21.28	11.3	12.37	10.92	7.2	6.81	6.8	9.25	7.75
Price/Tangible Book Value Low	23.21	13.54	7.25	13.7	30.99	17.42	9.3	8.36	8.82	7.04	5.23	4.5	4.65	6.72	5.4
Price/Sales	4.82	5.82	13.79	48.16	29.41	10.59	14.99	13.83	13.5	9.9	7.47	8.28	10.62	9.42	9.66
Price/Sales Average	6.39	6.58	12.62	36.28	28.94	12.68	12.69	13.97	11.39	10.53	6.96	7.87	8.86	10.54	9.45
Price/Sales High	8.55	9.17	16.69	50.41	33.53	17.96	16.79	16.26	13.92	12.82	8.27	9.31	10.78	12.17	11.07
Price/Sales Low	3.85	4.45	7.93	24.24	22.78	10.27	7.33	12.02	9.93	8.27	6	6.16	7.37	8.84	7.72
Price/Cash Flow	47.34	33.16	-275.45	-48.78	-83.09	76.35	44.14	33.17	35.82	18.88	21.41	17.91	29.64	-210.83	31.92
Price/Cash Flow Average	62.76	37.49	-252.2	-36.74	-81.74	91.39	37.38	33.51	30.22	20.09	19.93	17.03	24.71	-235.89	31.23
Price/Cash Flow High	83.92	52.31	-333.51	-51.06	-94.73	129.5	49.44	39.02	36.92	24.45	23.69	20.14	30.09	-272.18	36.59
Price/Cash Flow Low	37.78	25.35	-158.38	-24.55	-64.35	74.06	21.6	28.84	26.33	15.77	17.19	13.31	20.56	-197.82	25.52
Price/Free Cash Flow Average	38.57	29.63	-1,649.98	-40.34	-93.31	73.73	29.1	31.77	29.28	18.86	18.46	16.41	23.28	-16,138.87	28.12
Price/Free Cash Flow High	51.58	41.33	-2,181.88	-56.06	-108.13	104.47	38.49	36.99	35.77	22.95	21.94	19.41	28.34	-18,621.81	32.95
Price/Free Cash Flow Low	23.22	20.03	-1,036.12	-26.96	-73.46	59.74	16.82	27.34	25.51	14.8	15.92	12.83	19.37	-13,534.38	22.98
EV/Sales Average	6.48	6.84	12.57	36.66	29.19	12.58	12.27	13.29	10.81	9.72	6.19	6.8	7.89	10.29	9.19
EV/Sales High	8.64	9.44	16.64	50.79	33.79	17.87	16.37	15.59	13.33	12	7.5	8.24	9.82	11.91	10.82
EV/Sales Low	3.94	4.71	7.88	24.62	23.04	10.18	6.91	11.34	9.34	7.45	5.23	5.08	6.4	8.59	7.47
EV/EBITDA Average	35.61	120.4	-140.8	-36.8	-74.9	294.99	67.23	55.01	34.37	20.25	16.13	13.81	19.65	-4,327.27	23.16
EV/EBITDA High	47.46	166.13	-186.37	-50.99	-86.7	418.95	89.66	64.51	42.39	25	19.55	16.73	24.45	-5,009.61	27.25
EV/EBITDA Low	21.62	82.93	-88.2	-24.71	-59.11	238.63	37.88	46.95	29.7	15.53	13.64	10.32	15.94	-3,611.53	18.81
EV/EBIT Average	41.24	215.08	-97.31	-33.17	-64.85	1,912.43	77.73	61.01	37.42	21.02	16.86	14.29	20.59	-485.75	24.23
EV/EBIT High	54.96	296.76	-128.81	-45.96	-75.07	2,716.04	103.68	71.54	46.16	25.96	20.44	17.31	25.62	-562.35	28.51
EV/EBIT Low	25.04	148.13	-60.96	-22.28	-51.18	1,547.03	43.8	52.07	32.34	16.12	14.26	10.68	16.71	-405.41	19.68
Last Price	33.21	41.9	74.3	118.8	125.83	73.67	149.86	165.71	218.95	236.34	219.6	288.78	406.89	402.7	453.36
High Price	58.87	66.1	89.96	124.35	143.45	124.96	167.86	194.92	225.66	306.08	242.99	324.75	413	519.88	519.68
Enterprise Value Average	9,143	10,447	15,238	21,277	30,136	21,415	30,536	40,506	44,981	60,308	46,855	60,720	77,843	113,375	110,337
Enterprise Value High	12,184	14,414	20,170	29,481	34,881	30,414	40,727	47,503	55,486	74,476	56,791	73,564	96,869	131,252	129,828
Enterprise Value Low	5,552	7,195	9,545	14,290	23,781	17,324	17,206	34,573	38,873	46,255	39,620	45,370	63,165	94,622	89,637

Shares Outstanding	209	217	234	242	246	248	253	255	259	260	254	257	258	257	254
Diluted Weighted Avg Shares	209	212	225	235	241	245	253	259	261	263	260	259	260	258	258
Basic Weighted Avg Shares	205	212	225	235	241	245	249	254	257	260	258	256	258	258	256
Revenue per Share	6.88	7.2	5.39	2.47	4.28	6.96	10	11.98	16.21	23.88	29.39	34.87	38.3	42.73	46.94
EBITDA per Share	1.25	0.41	-0.48	-2.46	-1.67	0.3	1.83	2.9	5.1	11.46	11.27	17.17	15.37	-0.1	18.63
Operating Income per Share	1.08	0.23	-0.7	-2.73	-1.93	0.05	1.58	2.61	4.68	11.04	10.78	16.59	14.67	-0.91	17.81
Basic EPS, GAAP	0.14	-0.5	-1.98	-3.14	-2.31	-0.46	1.06	8.25	4.58	10.44	9.09	12.97	14.05	-2.08	15.46
Basic EPS from Cont Ops	0.2	0.15	-2.24	-3.15	-2.44	-0.34	0.37	8.21	4.58	10.44	9.09	12.97	14.05	-2.08	15.46
Diluted EPS, GAAP	0.14	-0.5	-1.98	-3.14	-2.31	-0.46	1.04	8.09	4.51	10.3	9.01	12.82	13.89	-2.08	15.32
Diluted EPS from Cont Ops	0.2	0.15	-2.24	-3.15	-2.44	-0.34	0.36	8.05	4.51	10.3	9.01	12.82	13.89	-2.08	15.32
Dividend per Share	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Cash Flow per Share	0.7	1.26	-0.27	-2.44	-1.51	0.96	3.4	5	6.11	12.52	10.26	16.13	13.73	-1.91	14.2
Free Cash Flow per Basic Share	0.24	0.93	-0.5	-2.65	-1.7	0.73	2.35	4.62	5.82	11.52	9.35	15.33	12.72	-3.79	12.49
Cash & Equivalents per Share	4.73	6.23	6.51	5.89	4.32	5.86	8.39	12.46	14.83	25.63	29.2	42.09	43.53	23.71	25.84
Book Value per Share	-16.66	-16.61	-17.63	-19.99	-21.79	-21.95	-20.56	-11.75	-7.21	3.31	12.43	25.48	39.37	37.26	53.04
Tangible Book Value per Share	1.14	2.37	5.89	4.37	3.14	4.1	7.89	17.24	18.24	28.03	33.75	47.72	60.74	56.21	67.08

Vertex Pharmaceuticals Incorporated

Profitability (USD)

Credit (USD)

Liquidity (USD)

Working Capital (USD)

Enterprise Value (USD)

Multiples (USD)

Per Share Data Items (USD)