Spyre Therapeutics, Inc. Financial Ratios — SYRE Stock

Profitability (USD)

	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Return on Common Equity (%)	- -	- -	- -	- -	-48.08	-75.32	-122.74	-80.93	-58.81	-124.87	- -	- -	- -
Return on Assets (%)	- -	-274.93	-54.32	-41.05	-44.24	-66.28	-97.26	-66.09	-48.46	-92.58	-164.06	-43.78	- -
Return on Capital (%)	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Return on Invested Capital (%)	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Gross Margin (%)	- -	- -	100	100	100	100	- -	- -	100	100	100	- -	- -
EBITDA Margin (%)	- -	- -	-184.49	-470.48	-526.94	-1,161.78	- -	- -	-341.92	-3,555.9	-14,426.64	- -	- -
Operating Margin (%)	- -	- -	-185.95	-473.34	-531.72	-1,169.32	- -	- -	-350.33	-3,640.23	-14,510.61	- -	- -
Incremental Operating Margin (%)	- -	- -	- -	- -	- -	- -	896.89	- -	- -	- -	- -	9,029.57	- -
Pretax Margin (%)	- -	- -	-185.62	-468.84	-523.27	-1,140.64	- -	- -	-350.39	-3,604.59	-38,241.08	- -	- -
Profit Margin (%)	- -	- -	-185.62	-468.84	-523.27	-1,140.64	- -	- -	-351.14	-3,598.75	-38,238.15	- -	- -
Net Income to Common Margin (%)	- -	- -	-189.37	-468.84	-523.27	-1,140.64	- -	- -	-351.14	-3,598.75	-65,767.16	- -	- -
Effective Tax Rate (%)	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Dvd Payout Ratio (%)	- -	- -	1.98	- -	- -	- -	- -	- -	- -	- -	41.86	21.94	- -
Sustainable Growth Rate (%)	- -	- -	- -	- -	-48.08	-75.32	-122.74	-80.93	-58.81	-124.87	- -	- -	- -

Credit (USD)

Credit Ratios API ChatGPT

	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Total Debt	- -	- -	- -	- -	- -	- -	5	5	5	5	- -	- -	- -
ST Debt	- -	- -	- -	- -	- -	- -	- -	- -	- -	1	- -	- -	- -
LT Debt	- -	- -	- -	- -	- -	- -	5	5	5	4	- -	- -	- -
Total Debt/EBITDA	- -	- -	- -	- -	- -	- -	-0.06	-0.07	-0.08	-0.06	- -	- -	- -
Net Debt/EBITDA	- -	0.29	2.61	2.19	0.47	0.5	0.24	1.12	0.24	0.42	1.48	0.43	0.39
Total Debt/EBIT	- -	- -	- -	- -	- -	- -	-0.06	-0.07	-0.08	-0.05	- -	- -	- -
Net Debt/EBIT	- -	0.29	2.59	2.18	0.46	0.49	0.24	1.11	0.23	0.41	1.47	0.43	0.39
EBITDA to Interest Expense	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
EBITDA-CapEx/Interest Expense	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
EBIT to Interest Expense	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Interest Expense	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Common Equity/Total Assets	-27.69	-391.57	-57.45	93.89	89.76	86.74	72.23	86.52	76.36	70.71	-0.27	59.49	71.92
Long-Term Debt/Equity (%)	- -	- -	- -	- -	- -	- -	7.84	3.67	5.51	7.96	- -	- -	- -
Long-Term Debt/Capital (%)	- -	- -	- -	- -	- -	- -	7.23	3.53	5.2	7.29	- -	- -	- -
Long-Term Debt/Total Assets (%)	- -	- -	- -	- -	- -	- -	5.66	3.17	4.21	5.63	- -	- -	- -
Total Debt/Equity (%)	- -	- -	- -	- -	- -	- -	8.43	3.9	6.03	9.2	- -	- -	- -
Total Debt/Capital (%)	- -	- -	- -	- -	- -	- -	7.77	3.75	5.69	8.43	- -	- -	- -
Total Debt/Total Assets (%)	- -	- -	- -	- -	- -	- -	6.09	3.37	4.6	6.51	- -	- -	- -
Net Debt to Equity	-144.33	-139.74	-81.14	-75.83	-25.46	-33.31	-32.05	-64.43	-18.04	-69.3	-102.65	-17.27	-11.98
Net Debt/Capital (%)	325.57	351.61	-430.16	-313.76	-34.16	-49.95	-41.95	-163.26	-20.5	-173.7	3,873.14	-20.87	-13.62
EBITDA	- -	-9	-11	-22	-27	-45	-80	-80	-64	-83	-128	-209	-220
EBITDA-CapEx	- -	-9	-11	-22	-28	-46	-81	-85	-65	-83	-128	-209	-220
Operating Income (Loss)	- -	-9	-11	-22	-28	-45	-80	-81	-66	-85	-129	-209	-220

Liquidity (USD)

Liquidity Ratios API ChatGPT

	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Cash Ratio	3.26	2.47	13.1	16.02	8.94	7.28	3.92	8.9	4.62	3.8	10.61	11.16	12.89
Current Ratio	3.26	2.58	15.17	16.75	9.77	7.49	4.06	9.11	4.91	4.25	10.68	11.26	13.25
Quick Ratio	3.26	2.47	13.78	16.32	9.48	7.28	3.92	8.9	4.66	3.83	10.61	11.16	12.89
CFO/Avg Current Liab	- -	-5.94	-6.13	-5.81	-5.13	-4.06	-4.59	-4.35	-2.94	-4.61	-4.28	-3.66	-3
Common Equity/Total Assets	-27.69	-391.57	-57.45	93.89	89.76	86.74	72.23	86.52	76.36	70.71	-0.27	59.49	71.92
Long-Term Debt/Equity (%)	- -	- -	- -	- -	- -	- -	7.84	3.67	5.51	7.96	- -	- -	- -
Long-Term Debt/Capital (%)	- -	- -	- -	- -	- -	- -	7.23	3.53	5.2	7.29	- -	- -	- -
Long-Term Debt/Total Assets (%)	- -	- -	- -	- -	- -	- -	5.66	3.17	4.21	5.63	- -	- -	- -
Total Debt/Equity (%)	- -	- -	- -	- -	- -	- -	8.43	3.9	6.03	9.2	- -	- -	- -
Total Debt/Capital (%)	- -	- -	- -	- -	- -	- -	7.77	3.75	5.69	8.43	- -	- -	- -
Total Debt/Total Assets (%)	- -	- -	- -	- -	- -	- -	6.09	3.37	4.6	6.51	- -	- -	- -
CFO/Total Liabilities	- -	-693.29	-430.67	-459.85	-428.83	-312.22	-284.36	-347.82	-206.72	-384.59	-63.3	-173.59	-270.61
CFO/CapEx	- -	-40.52	-52.8	-88.87	-39.77	-76.29	-44.03	-17.7	-93.75	-2,109.05	- -	- -	- -
Altman's Z-Score	0.24	-15.21	-0.55	7.72	7.14	7.56	0.11	7.33	0.12	-10.63	-0.33	7.01	22.72

Working Capital (USD)

Working Capital Ratios API ChatGPT

	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Accounts Receivable Turnover	- -	- -	7.17	3.18	2.42	2.53	- -	- -	- -	- -	- -	- -	- -
Days Sales Outstanding	- -	- -	50.9	114.83	150.52	144.48	- -	- -	- -	- -	- -	- -	- -
Inventory Turnover	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Days Inventory Outstanding	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Accounts Payable Turnover	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Accounts Payable Turnover Days	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Cash Conversion Cycle	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Inventory to Cash Days	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Inventories	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Raw Materials	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Work In Process	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Finished Goods	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Other Inventory	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -

Enterprise Value (USD)

Enterprise Value API ChatGPT

	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Market Capitalization	- -	- -	- -	58	90	181	222	377	234	29	776	1,403	2,561
- Cash & Cash Equivalents	5	3	29	48	13	22	19	90	15	35	189	89	86
+ Preferred Equity and Hybrid Capital	4	13	58	- -	- -	- -	- -	- -	- -	- -	185	156	156
+ Minority/Non Controlling Interest	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
+ Total Debt	- -	- -	- -	- -	- -	- -	5	5	5	5	- -	- -	- -
Enterprise Value	- -	11	25	-5	40	106	155	237	146	-22	622	956	1,961
Total Capital	3	2	36	63	50	67	65	145	89	55	184	518	715
Total Debt/Capital (%)	- -	- -	- -	- -	- -	- -	7.77	3.75	5.69	8.43	- -	- -	- -
Total Debt / EV	- -	- -	- -	- -	- -	- -	0.03	0.02	0.03	-0.21	- -	- -	- -
EV/Sales	- -	- -	4.15	- -	7.66	27.34	- -	- -	7.81	- -	701.58	- -	- -
EV/EBITDA	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
EV/EBIT	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
EV/Cash Flow to Firm	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
EV/Free Cash Flow to Firm	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Diluted Market Cap	- -	- -	- -	43	82	156	244	420	312	38	148	1,095	2,098
Diluted Enterprise Value	- -	11	29	-5	69	133	230	335	302	8	144	1,161	2,169
EV per Share	- -	23.47	55.23	- -	59.82	110.08	133.51	123.34	74.14	- -	17.24	15.86	25.08
TTM Sales	- -	- -	6	5	5	4	- -	- -	19	2	1	- -	- -
TTM EBITDA	- -	-9	-11	-22	-27	-45	-80	-80	-64	-83	-128	-209	-220
TTM Operating Income	- -	-9	-11	-22	-28	-45	-80	-81	-66	-85	-129	-209	-220
TTM Cash Flow to Firm	- -	-7	-11	-19	-25	-32	-66	-76	-54	-80	-100	-157	-169
TTM Free Cash Flow to Firm	- -	-7	-11	-19	-24	-32	-64	-71	-53	-80	-100	-157	-169

Multiples (USD)

Valuation Multiples API ChatGPT

	2013 Y	2014 Y	2015 Y	2016 Y	2017 Y	2018 Y	2019 Y	2020 Y	2021 Y	2022 Y	2023 Y	2024 Y	2025 Y
As of date	12/31/2013	12/31/2014	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025

Price/Free Cash Flow	- -	- -	- -	-2.29	-3.41	-4.91	-3.8	-5.88	-5.88	-0.47	-1.49	-6.96	-12.4
EV/EBIT	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Enterprise Value	- -	11	25	-5	40	106	155	237	146	-22	622	956	1,961
Low Price	- -	- -	- -	97.25	70.25	123.75	149.75	87.5	86.75	8.5	2.65	18.54	10.91
EV/Sales	- -	- -	4.15	- -	7.66	27.34	- -	- -	7.81	- -	701.58	- -	- -
EV/EBITDA	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Price/Earnings	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Price/Earnings Average	- -	- -	- -	-2.86	-2.75	-4.1	-3.15	-4.97	-7.05	-1.49	-0.13	-5.29	- -
Price/Earnings High	- -	- -	- -	-5.75	-4.52	-5.63	-3.86	-7.51	-8.78	-4.86	-0.28	-8.47	- -
Price/Earnings Low	- -	- -	- -	-1.76	-1.56	-2.32	-2.45	-2.31	-3.47	-0.34	-0.03	-3.27	- -
Price/Book Value	- -	- -	- -	0.93	1.79	2.68	3.7	2.7	2.79	0.58	-851.76	3.88	4.58
Price/Book Value Average	- -	- -	- -	1.35	1.64	3.13	3.74	2.58	4.15	1.93	-423.5	4.99	2.73
Price/Book Value High	- -	- -	- -	2.72	2.7	4.3	4.57	3.9	5.17	6.27	-949.91	7.99	4.94
Price/Book Value Low	- -	- -	- -	0.83	0.93	1.77	2.9	1.2	2.04	0.44	-104.89	3.09	1.52
Price/Tangible Book Value	- -	- -	- -	0.93	1.79	2.68	3.7	2.7	2.79	0.58	-851.76	3.88	4.58
Price/Tangible Book Value Average	- -	- -	- -	1.35	1.64	3.13	3.74	2.58	4.15	1.93	-423.5	4.99	2.73
Price/Tangible Book Value High	- -	- -	- -	2.72	2.7	4.3	4.57	3.9	5.17	6.27	-949.91	7.99	4.94
Price/Tangible Book Value Low	- -	- -	- -	0.83	0.93	1.77	2.9	1.2	2.04	0.44	-104.89	3.09	1.52
Price/Sales	- -	- -	- -	9.2	15.72	40.11	- -	- -	16.67	16.28	167.52	- -	- -
Price/Sales Average	- -	- -	- -	13.39	14.39	46.81	- -	- -	24.75	53.64	83.29	- -	- -
Price/Sales High	- -	- -	- -	26.98	23.66	64.27	- -	- -	30.84	174.79	186.83	- -	- -
Price/Sales Low	- -	- -	- -	8.23	8.17	26.51	- -	- -	12.17	12.3	20.63	- -	- -
Price/Cash Flow	- -	- -	- -	-2.26	-3.32	-4.84	-3.72	-5.54	-5.81	-0.47	-1.49	-6.96	-12.4
Price/Cash Flow Average	- -	- -	- -	-3.29	-3.04	-5.65	-3.75	-5.31	-8.63	-1.56	-0.74	-8.95	-7.39
Price/Cash Flow High	- -	- -	- -	-6.63	-5	-7.76	-4.6	-8.02	-10.76	-5.08	-1.66	-14.33	-13.36
Price/Cash Flow Low	- -	- -	- -	-2.02	-1.73	-3.2	-2.91	-2.47	-4.25	-0.36	-0.18	-5.54	-4.13
Price/Free Cash Flow Average	- -	- -	- -	-3.33	-3.12	-5.73	-3.84	-5.62	-8.73	-1.56	-0.74	-8.95	-7.39
Price/Free Cash Flow High	- -	- -	- -	-6.7	-5.13	-7.86	-4.7	-8.5	-10.87	-5.08	-1.66	-14.33	-13.36
Price/Free Cash Flow Low	- -	- -	- -	-2.04	-1.77	-3.24	-2.98	-2.61	-4.29	-0.36	-0.18	-5.54	-4.13
EV/Sales Average	- -	- -	4.77	8.05	13.4	48.49	- -	- -	18.04	28.61	430.97	- -	- -
EV/Sales High	- -	- -	4.77	26.68	23.61	68.73	- -	- -	22.61	122.55	972.24	- -	- -
EV/Sales Low	- -	- -	4.77	0.97	6.54	24.96	- -	- -	8.6	- -	103.37	- -	- -
EV/EBITDA Average	- -	-1.21	-2.58	-1.71	-2.54	-4.17	-2.63	-3.44	-5.28	-0.8	-2.99	-8.98	-7.27
EV/EBITDA High	- -	-1.21	-2.58	-5.67	-4.48	-5.92	-3.26	-5.73	-6.61	-3.45	-6.74	-14.18	-12.89
EV/EBITDA Low	- -	-1.21	-2.58	-0.21	-1.24	-2.15	-2	-1.03	-2.52	0.1	-0.72	-5.67	-4.2
EV/EBIT Average	- -	-1.2	-2.56	-1.7	-2.52	-4.15	-2.62	-3.4	-5.15	-0.79	-2.97	-8.98	-7.27
EV/EBIT High	- -	-1.2	-2.56	-5.64	-4.44	-5.88	-3.24	-5.66	-6.45	-3.37	-6.7	-14.18	-12.89
EV/EBIT Low	- -	-1.2	-2.56	-0.21	-1.23	-2.13	-1.99	-1.02	-2.46	0.09	-0.71	-5.67	-4.2
Last Price	- -	- -	- -	108.75	135.25	187.25	191	196.75	118.75	11.25	21.52	23.28	32.76
High Price	- -	- -	- -	318.75	203.5	300	236.25	284.5	219.75	120.75	24	47.97	35.31
Enterprise Value Average	- -	11	29	37	70	189	210	277	338	67	382	1,872	1,597
Enterprise Value High	- -	11	29	123	123	267	261	461	424	285	861	2,957	2,831
Enterprise Value Low	- -	11	29	4	34	97	160	83	161	-8	92	1,184	923

Shares Outstanding	- -	- -	- -	1	1	1	1	2	2	3	36	60	78
Diluted Weighted Avg Shares	- -	- -	- -	- -	1	1	1	2	3	3	7	47	64
Basic Weighted Avg Shares	- -	- -	- -	- -	1	1	1	2	3	3	7	47	64
Revenue per Share	- -	- -	13.31	11.82	8.6	4.67	- -	- -	7.13	0.69	0.13	- -	- -
EBITDA per Share	- -	-32.57	-24.55	-55.59	-45.32	-54.23	-62.53	-37.7	-24.36	-24.57	-18.53	-4.43	-3.43
Operating Income per Share	- -	-32.64	-24.75	-55.93	-45.74	-54.58	-62.86	-38.17	-24.96	-25.15	-18.64	-4.43	-3.43
Basic EPS, GAAP	- -	-37.93	-25.2	-55.4	-45.01	-53.25	-61.23	-37.89	-25.02	-24.86	-84.48	-5.67	- -
Basic EPS from Cont Ops	- -	-37.93	-24.71	-55.4	-45.01	-53.25	-61.23	-37.89	-25.02	-24.86	-49.12	-4.42	-2.42
Diluted EPS, GAAP	- -	-37.93	-25.2	-55.4	-45.01	-53.25	-61.23	-37.89	-25.02	-24.86	-84.48	-5.67	- -
Diluted EPS from Cont Ops	- -	-37.93	-24.71	-55.4	-45.01	-53.25	-61.23	-37.89	-25.02	-24.86	-49.12	-4.42	-2.42
Dividend per Share	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -	- -
Cash Flow per Share	- -	-26.89	-24.02	-48.1	-40.68	-38.65	-51.4	-35.49	-20.43	-23.77	-14.49	-3.35	-2.64
Free Cash Flow per Basic Share	- -	-27.55	-24.48	-48.64	-41.7	-39.16	-52.57	-37.5	-20.64	-23.78	-14.49	-3.35	-2.64
Cash & Equivalents per Share	10.05	5.72	72.32	118.2	75.43	77.17	61.84	76.25	47.17	21.31	9.41	10.01	9.68
Book Value per Share	-2.78	-25.09	-48.57	117.2	75.49	69.83	51.64	72.89	42.52	19.24	-0.03	6.01	7.15
Tangible Book Value per Share	-2.78	-25.09	-48.57	117.2	75.49	69.83	51.64	72.89	42.52	19.24	-0.03	6.01	7.15

Spyre Therapeutics, Inc.

Profitability (USD)

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Per Share Data Items (USD)