Upstream Bio, Inc.

UPB

UPBUpstream Bio, Inc. US flag

NASDAQ Global Select

7.63

USD

+0.38

- -

415.22MMarket Cap

Income Statement (USD)

API Chat

	2022 Y	2023 Y	2024 Y	2025 Y
Sales/Revenue/Turnover	1	2	2	3
+ Sales & Services Revenue	1	2	2	3
- Cost of Revenue	- -	- -	- -	- -
+ Cost of Goods & Services	- -	- -	- -	- -
Gross Profit	- -	- -	- -	- -
+ Other Operating Income	-1	-2	-2	-3
- Operating Expenses	25	42	80	163
+ Selling, General & Admin	6	11	17	26
+ Research & Development	19	32	63	137
+ Other Operating Expense	- -	- -	- -	- -
Operating Income (Loss)	-24	-40	-78	-160
- Non-Operating (Income) Loss	- -	-20	-15	-17
+ Interest Expense, Net	- -	-4	-12	-17
+ Interest Expense	- -	- -	- -	- -
- Interest Income	- -	4	12	17
+ Other Non-Op (Income) Loss	- -	-15	-3	- -
Pretax Income	-24	-21	-63	-143
- Income Tax Expense (Benefit)	- -	- -	- -	- -
- (Income) Loss from Affiliates	- -	- -	- -	- -
Income (Loss) from Cont Ops	-24	-21	-63	-143
- Net Extraordinary Losses (Gains)	- -	- -	- -	- -
+ Discontinued Operations	- -	- -	- -	- -
+ Extraord. & Accounting Changes	- -	- -	- -	- -
Income (Loss) Incl. MI	-24	-21	-63	-143
- Minority Interest	- -	- -	- -	- -
Net Income, GAAP	-24	-21	-63	-143
- Preferred Dividends	- -	18	14	- -
- Other Adjustments	- -	- -	- -	- -
Net Income Avail to Common, GAAP	-24	-38	-76	-143
EBIT	-24	-40	-78	-160
EBITDA	-24	-40	-78	-160
EBITDA Margin (%)	-1,972.11	-1,682.94	-3,277.43	-5,612.23
EBITA	-24	-40	-78	-160
Gross Margin (%)	100	100	100	100
Operating Margin (%)	-1,972.69	-1,685.46	-3,281.18	-5,618.82
Profit Margin (%)	-1,969.31	-862.9	-2,650.04	-5,026.03
Sales per Employee	- -	- -	- -	- -
Dividend per Share	- -	- -	- -	- -
Depreciation Expense	- -	- -	- -	- -
Basic Weighted Avg Shares	36	36	54	54
Basic EPS, GAAP	-0.66	-1.05	-1.43	-2.66
Basic EPS from Cont Ops	-0.66	-0.57	-1.17	-2.66
Diluted Weighted Avg Shares	36	36	54	54
Diluted EPS, GAAP	-0.66	-1.05	-1.43	-2.66
Diluted EPS from Cont Ops	-0.66	-0.57	-1.17	-2.66

Balance Sheet (USD)

API Chat

	2022 Y	2023 Y	2024 Y	2025 Y
Total Current Assets	18	117	479	352
+ Cash, Cash Equivalents & STI	17	110	470	342
+ Cash & Cash Equivalents	17	26	326	102
+ ST Investments	- -	84	145	240
+ Accounts & Notes Receiv	- -	- -	1	2
+ Accounts Receivable, Net	- -	- -	1	1
+ Notes Receivable, Net	- -	- -	- -	- -
+ Loans Receivable, Net	- -	- -	- -	- -
+ Other Receivable, Net	- -	- -	1	2
+ Inventories	- -	- -	- -	- -
+ Raw Materials	- -	- -	- -	- -
+ Work In Process	- -	- -	- -	- -
+ Finished Goods	- -	- -	- -	- -
+ Inventory Adjustments	- -	- -	- -	- -
+ Other Inventory	- -	- -	- -	- -
+ Other ST Assets	1	7	8	8
+ Misc ST Assets	- -	- -	- -	- -
+ Prepaid Expenses	- -	- -	- -	- -
+ ST Derivative & Hedging Assets	- -	- -	- -	- -
+ ST Assets Held-for-Sale	- -	- -	- -	- -
+ ST Deferred Tax Assets	- -	- -	- -	- -
Total Noncurrent Assets	- -	- -	3	2
+ Property, Plant & Equip, Net	- -	- -	2	2
+ Property, Plant & Equip	- -	- -	3	2
- Accumulated Depreciation	- -	- -	- -	- -
+ LT Investments & Receivables	- -	- -	- -	- -
+ LT Investments	- -	- -	- -	- -
+ LT Receivables	- -	- -	- -	- -
+ Other LT Assets	- -	- -	- -	- -
+ Total Intangible Assets	- -	- -	- -	- -
+ Goodwill	- -	- -	- -	- -
+ Other Intangible Assets	- -	- -	- -	- -
+ LT Deferred Tax Assets	- -	- -	- -	- -
+ LT Derivative & Hedging Assets	- -	- -	- -	- -
+ Misc LT Assets	- -	- -	- -	- -
Total Assets	18	117	482	354
+ Payables & Accruals	4	4	7	9
+ Accounts Payable	1	2	4	3
+ Accrued Taxes	- -	- -	- -	- -
+ Interest & Dividends Payable	- -	- -	- -	- -
+ Other Payables & Accruals	3	2	3	6
+ ST Debt	- -	- -	1	1
+ ST Borrowings	- -	- -	- -	- -
+ ST Finance Leases	- -	- -	1	1
+ Other ST Liabilities	1	2	3	4
+ Deferred Revenue	- -	- -	- -	- -
+ Derivatives & Hedging	- -	- -	- -	- -
+ Deferred Tax Liabilities	- -	- -	- -	- -
+ Misc ST Liabilities	1	2	3	4
Total Current Liabilities	5	7	11	13
+ LT Debt	- -	- -	1	1
+ LT Borrowings	- -	- -	- -	- -
+ LT Finance Leases	- -	- -	1	1
+ Other LT Liabilities	120	234	- -	- -
+ Accrued Liabilities	- -	- -	- -	- -
+ Pension Liabilities	- -	- -	- -	- -
+ Deferred Revenue	- -	- -	- -	- -
+ Deferred Tax Liabilities	- -	- -	- -	- -
+ Derivatives & Hedging	- -	- -	- -	- -
+ Misc LT Liabilities	120	234	- -	- -
Total Noncurrent Liabilities	120	234	1	1
Total Liabilities	125	240	12	14
+ Preferred Equity and Hybrid Capital	- -	- -	- -	- -
+ Share Capital & APIC	1	5	661	673
+ Common Stock	- -	- -	- -	- -
+ Additional Paid in Capital	1	5	661	673
- Treasury Stock	- -	- -	- -	- -
+ Retained Earnings	-107	-128	-191	-334
+ Other Equity	- -	- -	- -	1
Equity Before Minority Interest	-106	-123	470	340
+ Minority/Non Controlling Interest	- -	- -	- -	- -
Total Equity	-106	-123	470	340
Total Liabilities & Equity	18	117	482	354
Shares Outstanding	51	51	54	54
Number of Employees	- -	- -	- -	- -
Capital Leases - Total	- -	- -	2	1
Net Debt	-17	-26	-326	-102
Net Debt to Equity	16.06	20.98	-69.36	-29.9
Tangible Common Equity Ratio	-574.49	-105.06	97.54	96.04
Current Ratio	3.77	17.96	44.63	26.15
Cash Conversion Cycle	- -	- -	- -	- -

Cash Flow Statement (USD)

API Chat

	2022 Y	2023 Y	2024 Y	2025 Y
+ Net Income	-24	-21	-63	-143
+ Depreciation & Amortization	- -	- -	- -	- -
+ Non-Cash Items	1	-13	2	9
+ Stock-Based Compensation	1	3	6	10
+ Deferred Income Taxes	- -	- -	- -	- -
+ Asset Impairment Charge	- -	- -	- -	- -
+ Other Non-Cash Adj	- -	-17	-4	-1
+ Chg in Non-Cash Work Cap	3	-4	2	1
+ (Inc) Dec in Accts Receiv	- -	- -	-1	- -
+ (Inc) Dec in Inventories	- -	- -	- -	- -
+ (Inc) Dec in Prepaid Assets	-1	-6	-1	-2
+ Inc (Dec) in Accts Payable	4	2	4	3
+ Inc (Dec) in Other	- -	- -	- -	-1
+ Net Cash From Disc Ops	- -	- -	- -	- -
Cash from Operating Activities	-19	-38	-59	-133
+ Change in Fixed & Intang	- -	- -	- -	- -
+ Disp in Fixed & Intang	- -	- -	- -	- -
+ Disp of Fixed Prod Assets	- -	- -	- -	- -
+ Disp of Intangible Assets	- -	- -	- -	- -
+ Acq of Fixed & Intang	- -	- -	-1	- -
+ Acq of Fixed Prod Assets	- -	- -	-1	- -
+ Acq of Intangible Assets	- -	- -	- -	- -
+ Cash (Repurchase) of Equity	- -	- -	273	- -
+ Increase in Capital Stock	- -	- -	273	- -
+ Decrease in Capital Stock	- -	- -	- -	- -
+ Net Change in LT Investment	- -	-83	-59	-93
+ Dec in LT Investment	- -	46	232	293
+ Inc in LT Investment	- -	-129	-291	-386
+ Net Cash From Acq & Div	- -	- -	- -	- -
+ Cash from Divestitures	- -	- -	- -	- -
+ Cash for Acq of Subs	- -	- -	- -	- -
+ Cash for JVs	- -	- -	- -	- -
+ Other Investing Activities	- -	- -	- -	- -
+ Net Cash From Disc Ops	- -	- -	- -	- -
Cash from Investing Activities	- -	-83	-59	-93
+ Dividends Paid	- -	- -	- -	- -
+ Net Cash From Debt	- -	- -	- -	- -
+ Cash From Debt	- -	- -	- -	- -
+ Repayments of Debt	- -	- -	- -	- -
+ Other Financing Activities	10	130	146	2
+ Net Cash From Disc Ops	- -	- -	- -	- -
Cash from Financing Activities	10	130	419	2
Effect of Foreign Exchange Rates	- -	- -	- -	- -
Net Changes in Cash	-9	9	300	-224
EBITDA	-24	-40	-78	-160
EBITDA Margin (%)	-1,972.11	-1,682.94	-3,277.43	-5,612.23
Free Cash Flow	-19	-38	-60	-133
Net Cash Paid for Acquisitions	- -	- -	- -	- -
Free Cash Flow to Firm	- -	- -	- -	- -
Free Cash Flow to Equity	- -	-56	-73	-133
Free Cash Flow per Basic Share	-0.53	-1.05	-1.11	-2.48
Price/Free Cash Flow	- -	- -	-15.02	-10.98
Cash Flow to Net Income	0.8	1.85	0.94	0.93
Capital Expenditures	- -	- -	-1	- -